Circulating miRNAs miR-34a and miR-150 associated with colorectal cancer progression

BMC Cancer

Table 3 Fold changes and associated p-values for miR-34a, miR-150, and miR-923 in the validation cohort

	miR-34a		miR-150		miR-923
	FC	P value	FC	P value	FC	P value
Normal vs Polyp	−1.3	0.286	1.52	0.218	1.24	0.537
Normal vs Adenoma	2.09	0.028	1.68	0.160	1.19	0.537
Normal vs Early Stage Cancer	2.84	0.002	−1.03	0.800	1.19	0.675
Normal vs Advanced Cancer	1.8	0.081	−1.52	0.282	−1.7	0.537
Polyp vs Adenoma	2.71	0.002	1.11	0.735	−1.04	0.904
Polyp vs Early Stage Cancer	3.69	0.000	−1.57	0.160	−1.05	0.779
Polyp vs Advanced Cancer	2.34	0.006	−2.31	0.007	−2.11	0.113
Adenoma vs Early Stage Cancer	1.36	0.381	−1.73	0.104	−1.01	0.867
Adenoma vs Advanced Cancer	−1.16	0.691	−2.55	0.001	−2.03	0.113
Early Stage Cancer vs Advanced Cancer	−1.58	0.169	−1.47	0.529	−2.02	0.113
Non-Cancer vs Early Stage Cancer	3.07	0.000	1.42	0.160	1.19	0.675
Non-Cancer vs Cancer	2.62	0.001	1.29	0.013	−1.11	0.779
Normal & Polyp vs Adenoma	1.9	0.002	1.98	0.282	1.08	0.537

Bold text denotes significant comparisons. Non-Cancer comprises normal, polyp & adenoma groups, Cancer comprises both early stage & advanced cancer groups.

ISSN: 1471-2407