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Table 2 Patient characteristics of the study group and reference group

From: Impact of delays in initiating postoperative chemoradiation while determining the MGMT promoter-methylation statuses of patients with primary glioblastoma

 

Study group in absolut numbers (%)

Reference group in absolut numbers (%)

Gender

Female

16 (32)

45 (35.4)

Male

34 (68)

82 (64.6)

Age in years [range]

58,9 [30.3–75.9]

58.7 [20.3–75.5]

Median KPS [range]

90 [60–100]

90 [70–100]

MGMT-promoter-status

MGMT-status not determined

0 (0)

95 (74.8)

MGMT-status determined

50 (100)

32 (25.2)

MGMT-promoter methylated

18 (36)

14 (43.8)

MGMT-promoter not methylated

32 (64)

18 (56.2)

Resection status

Gross Total resection

18 (36)

58 (45.7)

Subtotal resection

30 (60)

60 (47.2)

Biopsy

2 (4)

9 (7.1)

Temozolomide therapy

26 (52)

127 (100)

Study medication

33 (66)

n.e.

Median delay to RT in days [range]

35 [18–49]

27 [5–98]

  1. Abbreviations: MGMT: O6-methylguanine-DNA-methyltransferase, KPS: Karnofsky performance status; RT: Radiation therapy
  2. Numbers in parentheses (*) are the percentages