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Table 3 Univariate proportional-hazards regression analysis of cofactors on progression-free survival in glioblastoma patients

From: Impact of delays in initiating postoperative chemoradiation while determining the MGMT promoter-methylation statuses of patients with primary glioblastoma

Cofactors

HR

95 % CI

P value

Study group

Age <60 years

0.73

0.39–1.35

0.31

Karnofsky Performance Status >70

0.65

0.25–1.67

0.37

Resection

0.24

0.03–1.92

0.18

Gross Total Resection

0.91

0.48–1.74

0.77

Study medication

1.19

0.63–2.26

0.59

MGMT promoter methylation

1.23

0.64–2.35

0.54

Reference group

Age <60 years

1.07

0.70–1.64

0.76

Karnofsky Performance Status >70

n.e.

n.e.

n.e.

Resection

1.27

0.47–3.48

0.64

Gross total Resection

0.85

0.56–1.29

0.45

MGMT promoter methylation

0.35

0.15–0.86

0.02

  1. Abbreviations: CI = Confidence interval; HR = Hazard ratio; SVZ = Subventricularzone; MGMT = O6-methylguanine-DNA methyltransferase