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Table 1 Correlation between ADORA2B expression and clinical classification

From: Adenosine A2b receptor promotes progression of human oral cancer

Clinical classification

Total

Results of immunostaining

p value

No. patients (%)

ADORA2B negative

ADORA2B positive

Age at surgery (years)

 <60

27

7 (26)

20 (74)

0.95

 ≧60, <70

26

8 (31)

18 (69)

 ≧70

47

13 (28)

34 (72)

Gender

 Male

64

21 (33)

43 (67)

0.24

 Female

36

7 (19)

29 (81)

T-primary tumor

 T1

8

3 (38)

5 (62)

0.02*

 T2

60

22 (37)

38 (63)

 T3

15

2 (13)

13 (87)

 T4

17

1 (6)

16 (94)

 T1 + T2

58

25 (43)

33 (57)

0.01*

 T3 + T4

32

3 (10)

29 (90)

N-regional lymph node

 N (negative)

58

14 (24)

44 (76)

0.39

 N (positive)

42

14 (33)

28 (67)

Stage

 I

7

3 (43)

4 (57)

0.54

 II

38

11 (29)

27 (71)

 III

17

4 (24)

13 (76)

 IV

38

10 (26)

28 (74)

Histopathologic type

 Well

64

15 (23)

49 (77)

0.25

 Moderately

31

11 (35)

20 (65)

 Poorly

5

2 (40)

3 (60)

Tumor site

 Gingiva

35

11 (31)

24 (69)

0.84

 Tongue

50

12 (24)

38 (76)

 Buccal mucosa

9

2 (22)

7 (78)

 Oral floor

6

3 (50)

3 (50)

  1. p < 0.05