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Table 4 Top 10 significantly enriched pathways found in genes commonly differentially expressed between WTtu_WTn and i) hiTAgtu_WTn or ii) loTAgtu_WTn

From: Consistent gene expression profiles in MexTAg transgenic mouse and wild type mouse asbestos-induced mesothelioma

Pathway

i) hiTAgtu and WTtu

ii) loTAgtu and WTtu

 

p-value

p-value

Cell cycle

0.0

0.0

G1 to S cell cycle control

0.0

0.0

DNA replication

1.760E–29

0.0

Mismatch repair

3.287E–9

1.59E–09

Homologous recombination

2.520E–6

4.66E–05

Purine metabolism

1.287E–5

0.005

mRNA processing

3.887E–5

6.08E–06

Hedgehog signaling pathway

6.695E–4

0.005

Complement activation, classical pathway

0.002

0.003

Nucleotide metabolism

0.004

0.003