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Table 1 Clinical and pathologic characteristics of the study cases

From: Genetic heterogeneity of actionable genes between primary and metastatic tumor in lung adenocarcinoma

   

n = 41

Age (mean ± SD); yrs

 

59.7 ± 11.06

Gender

   
 

Male

 

13

 

Female

 

28

Smoking status

   
 

Never smoker

33

 

Current smoker

3

 

Ex-smoker

5

pStage

   
 

IIA

 

17

 

IIB

 

1

 

IIIA

 

23

Driver mutation

   
 

ALK fusion (n = 1)

 
 

EGFR mutation (n = 35)a

 
  

L858R

16

  

L861Q

1

  

E19del

19

  

E20ins

1

  

G719Ser

2

 

KRAS (n = 5)

 
  

G12V

2

  

G12C

1

  

G12D

2

Histologic subtypes

  
 

Lepidic predominant

1

 

Acinar predominant

29

 

Papillary and micropapillary predominant

8

 

Solid predominant with mucin production

2

 

Invasive mucinous adenocarcinoma

1

  1. aFour cases harbored double EGFR driver mutations (See the Additional file 1)