| Grade 1 | Grade 2 | Grade 3 | Grade 4 |
---|---|---|---|---|
Local treatment | • No treatment is required | • Keep the site clean and dry | • Keep the site clean and dry | • Keep the site clean and dry |
• Avoid rubbing and maintain moisture and hygiene | • Topical treatment with antiseptics/antibiotics/steroids is recommended | • Topical treatment with antiseptics/antibiotics/steroids is recommended | • Topical treatment with antiseptics/antibiotics/steroids is recommended | |
• Topical treatment with antiseptics/antibiotics/steroids may help | ||||
Systemic treatment | • No treatment is required | • No treatment is required | • Oral antibiotics, pain-killers, corticosteroids or antihistamines for symptom relief | • Oral antibiotics, pain-killers, corticosteroids or antihistamines for symptom relief |
• Regular monitoring is recommended | • Oral antibiotics, pain-killers, corticosteroids or antihistamines for symptom relief | |||
• Temporary discontinuation or delay of cetuximab treatment | ||||
• Temporary discontinuation of cetuximab and radiation treatment |