Table 2 Histological diagnosis and clinical management

Total biopsy

68 (100)

12 (17.6)

56 (82.3)

Number of biopsy per patient

1

17 (37,7)

3 (17.6)

14 (82.3)

2

17 (37,7)

3 (17.6)

14 (82.3)

≥3

11 (24,4)

1 (9.1)

10 (90.9)

Histological diagnosis

Drug Hepatotoxicity

2 (3,9)

1 (50.0)

1 (50.0)

AIH

1 (1,4)

-

1 (100)

GVHD

24 (35,2)

4 (16,7)

20 (83.3)

GVHD + IO

19 (27,9)

3

16

GVHD + IO + Infection

1 (1,4)

-

1 (100)

GVHD + IO + MD

2 (2,9)

-

2 (100)

Infection

4 (5,8)

1 (25.0)

3 (75.0)

IO + Drug toxicity

4 (5,8)

1 (25.0)

3 (75.0)

IO + Infection

1 (1,4)

1 (100)

-

IO + MD

1 (1,4)

-

1 (100)

Iron overload

6 (8,8)

1 (16.7)

5 (83.3)

Metabolic Disorders

2 (2,9)

0

2 (100)

Normal

1 (1,4)

0

1 (100)

Changes in clinical management

No

32 (47,1)

3 (9.4)

29 (90.6)

Yes

36 (52,9)

9 (25.0)

27 (75.0)

Outcome

Improved

33 (48,5)

6 (18.2)

27 (81.8)

Recovered

13 (19,1)

2 (15.4)

11 (84.6)

Not changed

19 (27,9)

2 (10.5)

17 (89.5)

Worsened

1 (1,4)

1 (100)

0

Death

2 (2,9)

1 (50.0)

1 (50.0)