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Fig. 4 | BMC Cancer

Fig. 4

From: A radiosensitizing effect of RAD51 inhibition in glioblastoma stem-like cells

Fig. 4

Chemical inhibitior of RAD51, RI-1, selectively radiosensitizes GSCs from group 2. Comet assay was performed on GSCs from group 1 (GSC-1 and - 11) (a) and group 2 (GSC-6 and -14) (b) treated for 24 h with 10 μM RI-1 before undergoing 16Gy IR. Data are given as a percentage of olive tail moment (OTM) normalized to control (***p < 0.001, **p < 0.01 versus control cells, ns = no significant). c Apoptosis was measured in both groups 7 days after treatment with 10 μM RI-1 and IR. Annexin V/7-AAD labeling was analyzed by flow cytometry (**p < 0.01, ns = no significant)

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