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Table 4 Factors associated with the likelihood of no active treatment in men with PCa from clinical registries in SA and Victoria

From: A retrospective analysis of Victorian and South Australian clinical registries for prostate cancer: trends in clinical presentation and management of the disease

 

Univariate model

Multivariate model

Factors

Odds Ratio

CI at 95 %

Odds Ratio

CI at 95 %

Year of Diagnosis

 2009 (Ref)

1

 

1

 

2010

1.16

0.98–1.37

1.26

1.02–1.55

2011

1.32

1.13–1.53

1.43

1.18–1.73

2012

1.37

1.18–1.59

1.82

1.51–2.21

2013

1.43

1.23–1.66

2.63

2.16–3.22

Age Group

  < 55 (Ref)

1

 

1

 

56–65

1.29

1.11–1.49

1.48

1.24–1.76

65–75

1.38

1.19–1.59

2.03

1.69–2.44

   > 75

2.01

1.71–2.36

5.83

4.56–7.45

State

 SA (Ref)

1

 

1

 

Victoria

1.74

1.54–1.95

1.49

1.16–1.65

Residential area

 Metropolitan (Ref)

1

 

1

 

 Regional/Rural

1.07

0.97–1.18

1.02

0.88–1.19

SEIFA

 Lowest 0–20 % (Ref)

1

 

1

 

 Lowest 21–40 %

0.96

0.81–1.14

0.85

0.69–1.07

 Lowest 41–60 %

0.97

0.82–1.15

0.97

0.77–1.22

 Highest 61–80 %

1.04

0.88–1.22

0.98

0.79–1.21

Highest 81–100 %

1.28

1.11–1.48

1.32

1.07–1.63

Method of diagnosis

 TRUS (Ref)

1

 

1

 

TURP

5.23

4.61–5.93

6.19

5.08–7.54

 Other

0.80

0.65–0.98

1.27

0.93–1.74

PSA (ng/mL)

  < 4 (Ref)

1

 

1

 

4.01–10

0.81

0.73–0.91

1.15

0.89–1.34

10.01–20

0.62

0.53–0.72

1.65

0.92–2.07

   > 20.01

0.36

0.29–0.44

1.31

0.89–1.91

Grade Group

 Grade Group 1 (Gleason score ≤ 6) [Ref]

1

 

1

 

 Grade Group 2 (Gleason score 3 + 4)

0.19

0.17–0.22

0.33

0.27–0.42

 Grade Group 3 (Gleason score 4 + 3)

0.09

0.07–0.12

0.13

0.09–0.17

 Grade Group 4 (Gleason score 8)

0.06

0.05–0.08

0.08

0.05–0.13

 Grade Group 5 (Gleason score >8)

0.07

0.06–0.09

0.07

0.05–0.12

NCCN Risk

 Low (Ref)

1

 

1

 

Intermediate

0.17

0.15–0.19

0.35

0.28–0.44

High

0.09

0.08–0.12

0.23

0.15–0.34

V.high/Metastatic

0.02

0.02–0.06

0.06

0.03–0.11

  1. SA South Australia, SEIFA Socio-Economic Index of Advantage and Disadvantage, NCCN National Comprehensive Cancer Network, GS Gleason Score, PSA Prostate Specific Antigen, TURP Transurethral Resection of the Prostate, TRUS Transrectal Ultrasonography of the Prostate
  2. Significant rows are highlighted in bold