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Fig. 6 | BMC Cancer

Fig. 6

From: Identification of epigenetic factors regulating the mesenchyme to epithelium transition by RNA interference screening in breast cancer cells

Fig. 6

Pharmacological inhibition of DOT1L induces E-cadherin and CD24 expression in MDA-MB-231 in vitro. Cells were treated with dose effects of EPZ-5676 (0.1 μM, 1 μM, 10 μM) or 0.1 % DMSO for the indicated days (noted d), followed by mRNA extraction and RT-qPCR with specific primers. a E-CAD expression relative to non treated cells. b CD24 expression relative to non treated cells. Data in a and b are the mean of RT-qPCR replicates from a representative experiment, and error bars indicate SEM. The experiments were run 2 times

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