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Table 1 Baseline characteristics and treatment outcome of TNBC patients treated with neoadjuvant chemotherapy (N = 54)

From: Body mass index modifies the relationship between γ-H2AX, a DNA damage biomarker, and pathological complete response in triple-negative breast cancer

Age at diagnosis

 

median (min-max) [IQrange]

49.2 (26.7–76.6) [45.3–60.3]

 <49

25 (46.3)

 ≥49

29 (53.7)

Stage

 II

18 (33.3)

 III

36 (66.7)

Grade

 1–2

22 (40.7)

 3

32 (59.3)

Ki-67

median (min-max) [IQrange]

70.0 (10.0–90.0) [43.7–80.0]

Chemotherapy

 Sequential

47 (87.0)

 Concomitant

7 (13.0)

pCR

 No

37 (68.5)

 Yes

17 (31.5)

BMI

 median (min-max) [IQrange]

23.9 (17.5–41.6) [21.7–25.9]

  < 25

31 (57.4)

  ≥ 25

23 (42.6)

γ-H2AX

 Low

25 (46.3)

 High

29 (53.7)

pChk1

 Neg

16 (29.6)

 Pos

38 (70.4)