Fig. 5

Comparative analysis of MV-mRNAs previously identified in other EVs, prostate cancer cell lines, and prostate benign and malignant tissues. a Heat map displaying the presence (blue) or absence (white) of the eight commonly identified mRNAs for the ETV1, FASN, RBM39, CCND2, ERG, GNRH1, HAL and LGALS4 genes in eleven different microarray studies of mRNA content of EVs from EVpedia database. blue = identified with a false positive ration (FPR) <0.05; light blue = identified with a FPR >0.05; white = not identified. b Heat map showing the expression of 14 genes in LNCaP, PC-3 and DU-145 cell lines from a dataset with accession number GSE36720. c Heat map displaying the differential expression of the mRNAs of eight genes in malignant prostate tissue as compared to benign prostate tissue. Dataset with accession number GSE55945. Results between different microarray studies are not comparable