Fig. 3

Phagocytic and chemotactic incapacity in macrophages following MP exposure. THP-1 macrophages were assessed after 24 h for their ability to phagocytise PE-labelled beads by flow cytometry following (a) 4 h MP co-culture or (b) 24 h MP co-culture. c THP-1 macrophages were assessed at 24 h following a 4 h MP co-culture for their ability to migrate through a transwell membrane (8 μm). Data was analysed using the BD LSR II, flow cytometer. Data represents mean ± SEM values of three independent experiments. Student’s unpaired two tailed T-test with Welch’s correction was used for A and B and One way Annova used for C. *P < 0.05, **P < 0.01 and ****P < 0.0001