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Fig. 4 | BMC Cancer

Fig. 4

From: Acetazolamide potentiates the anti-tumor potential of HDACi, MS-275, in neuroblastoma

Fig. 4

AZ and/or MS-275 treatments decreased migration capacity of NB cells. a-b represent the wound healing assay for AZ (40 μM), MS-275 (1.5 μM) and AZ + MS-275 (40 μM + 0.75 μM) treatment compared to untreated group in SH-SY5Y cells. AZ caused a 10 ± 0.35% (p = 0.025, 48 h) and 12 ± 0.85% (p < 0.01,72 h) inhibition while MS-275 caused a 42 ± 0.13% (p < 0.001, 48 h) and 65 ± 0.30% (p < 0.001, 72 h) inhibition in migration. The AZ + MS-275 combination significantly inhibited migration with a 63 ± 0.37% (p < 0.001, 48 h) and 74 ± 0.25% (p < 0.001, 72 h) inhibition in migration ability

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