Table 5 Percentage of tumor volume, weight and expression of CD31 values
From: Acetazolamide potentiates the anti-tumor potential of HDACi, MS-275, in neuroblastoma
Treatment modality | Concentration (mg/kg) | % Inhibition of tumor volume (p value) | % Reduction in tumor weight (p value) | % Expression of CD31 marker (p value) |
|---|---|---|---|---|
AZ | 40 | 13 ± 0.29 (p = 0.009) | 29 ± 0.2 (p = 0.193) | 87 ± 0.98 (p = 0.006) |
MS-275 | 20 | 43 ± 0.50 (p = 0.001) | 83 ± 0.74 (p < 0.001) | 48 ± 0.94 (p = 0.008) |
AZ + MS-275 | 40 + 20 | 60 ± 0.48 (p = 0.001) | 89.5 ± 0.94 (p < 0.001) | 27 ± 0.92 (p < 0.001) |