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Table 8 Percentage of HIF-1α and CAIX positive cells values of SH-SY5Y tumors

From: Acetazolamide potentiates the anti-tumor potential of HDACi, MS-275, in neuroblastoma

Treatment modality

% Expression of HIF-1α positive cells (p value)

% Expression of CAIX positive cells (p value)

AZ

71 ± 0.70 (p < 0.001)

82 ± 0.11 (p = 0.0138)

MS-275

34 ± 0.23 (p < 0.001)

27 ± 0.33 (p < 0.001)

AZ + MS-275

17 ± 0.73 (p < 0.001)

10 ± 0.16 (p < 0.001)

  1. Table 8 shows the percentage of SH-SY5Y tumors by AZ (40 mg/kg), MS-275 (20 mg/kg) and AZ + MS-275 (40 + 20 mg/kg) treatments (14D)