From: In search of druggable targets for GBM amino acid metabolism
 | Enzymes for which … | ||
---|---|---|---|
higher expression is linked to poor survival | lower expression is linked to poor survival | expression is not correlated with survival | |
Enzymes with higher expression in GBM | BCAT1 a ASLa LAP3 PIPOX a GFPT2 DDO a FAH | DDAH2 SHMT2 TYMS SHMT1 | TDO2 IDO1 |
Enzymes with expression as in normal brain | CNDP2 GSS a GLUL (GS) | PHGDH SEPHS1 ABAT ALT (GPT) AGXT | ASNS MTR |
Enzymes with lower expression in GBM | PRODH a ASS1 a | AST (GOT1) ASPA a PAH | GLUD1/GLUD2 GAD1/GAD2 GLS TH |