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Table 3 Hazard ratios (HRs) a and 95% confidence intervals (CIs) for the association between metabolic dysregulation factors and cancer mortality

From: Metabolic dysregulation and cancer mortality in a national cohort of blacks and whites

 

Black

(N = 287) b

White

(N = 497) b

All

(N = 784) b

p valueinteraction c

Obesity

 1st Quartile (Ref)

Referent

Referent

Referent

0.25

 2nd Quartile

0.69 (0.48–0.98)

0.77 (0.60–0.99)

0.77 (0.62–0.94)

 

 3rd Quartile

0.57 (0.37–0.88)

0.68 (0.50–0.94)

0.72 (0.56–0.93)

 

 4th Quartile

0.63 (0.38–1.06)

0.71 (0.47–1.07)

0.84 (0.61–1.16)

 

Cholesterol

 1st Quartile (Ref)

Referent

Referent

Referent

0.27

 2nd Quartile

0.92 (0.66–1.28)

0.68 (0.52–0.88)

0.77 (0.63–0.94)

 

 3rd Quartile

0.76 (0.53–1.09)

0.83 (0.64–1.08)

0.81 (0.65–0.99)

 

 4th Quartile

0.87 (0.61–1.25)

0.86 (0.66–1.13)

0.86 (0.70–1.07)

 

Blood Pressure

 1st Quartile (Ref)

Referent

Referent

Referent

0.55

 2nd Quartile

1.02 (0.68–1.54)

1.06 (0.81–1.39)

1.06 (0.85–1.32)

 

 3rd Quartile

0.89 (0.57–1.39)

0.87 (0.63–1.21)

0.89 (0.69–1.16)

 

 4th Quartile

0.78 (0.48–1.25)

0.92 (0.64–1.31)

0.86 (0.65–1.14)

 

Lipids

 1st Quartile (Ref)

Referent

Referent

Referent

0.55

 2nd Quartile

1.28 (0.91–1.79)

0.95 (0.70–1.29)

1.07 (0.85–1.33)

 

 3rd Quartile

1.12 (0.73–1.74)

0.92 (0.64–1.33)

1.00 (0.76–1.32)

 

 4th Quartile

1.42 (0.86–2.32)

1.20 (0.81–1.79)

1.30 (0.96–1.77)

 

Height

 1st Quartile (Ref)

Referent

Referent

Referent

0.07

 2nd Quartile

0.90 (0.60–1.33)

1.00 (0.74–1.36)

0.97 (0.77–1.23)

 

 3rd Quartile

1.34 (0.89–2.03)

0.86 (0.61–1.23)

1.04 (0.80–1.36)

 

 4th Quartile

0.91 (0.56–1.49)

0.83 (0.56–1.22)

0.88 (0.65–1.19)

 

Glucose

 1st Quartile (Ref)

Referent

Referent

Referent

0.58

 2nd Quartile

1.28 (0.88–1.85)

1.20 (0.91–1.58)

1.23 (0.99–1.54)

 

 3rd Quartile

1.15 (0.78–1.68)

1.23 (0.93–1.62)

1.21 (0.97–1.51)

 

 4th Quartile

1.57 (1.10–2.23)

1.21 (0.90–1.62)

1.35 (1.08–1.69)

 

# Factor Variables in 4th Quartile

 0 (Referent)

Referent

Referent

Referent

0.08

 1

0.83 (0.56–1.21)

1.60 (1.16–2.19)

1.27 (0.99–1.62)

 

 2

0.92 (0.62–1.36)

1.52 (1.08–2.14)

1.25 (0.97–1.62)

 

 3+

1.02 (0.65–1.62)

1.39 (0.94–2.07)

1.23 (0.91–1.66)

 
  1. aAnalysis based on 19,963 REGARDS participants with non-missing data on all factor analysis component variables. Models adjusted for age, sex, race (all model only), education, region, income, tobacco use, alcohol use, and baseline chronic medical conditions, and hs-CRP
  2. b N = number of cancer death events
  3. c Interaction significance between race*factor using Wald test. Bold indicates statistically significant at 0.05 alpha level