Fig. 2From: Impact of RUNX2 on drug-resistant human pancreatic cancer cells with p53 mutationsFunctional interplay among p53 family members. Mutant p53 inhibits pro-apoptotic wild-type p53, TAp73 and TAp63 through the direct interaction, and thus contributes to the acquisition and/or maintenance of the serious drug-resistant phenotype of malignant tumorsBack to article page