Fig. 3From: Impact of RUNX2 on drug-resistant human pancreatic cancer cells with p53 mutationsRUNX2 prohibits pro-apoptotic TAp63 in p53-mutated pancreatic cancer cells. RUNX2 collaborates with mutant p53 to inhibitpro-apoptotic TAp63 in pancreatic cancer Panc-1 cells exposed to GEM. In addition to the direct interaction, RUNX2 trans-represses TAp63 transcriptionBack to article page