Survival and clinical outcomes of patients with melanoma brain metastasis in the era of checkpoint inhibitors and targeted therapies

Table 5 Multivariate Cox regression analysis of association of various clinical factors with overall survival in melanoma patients with brain metastasis

Variable	Chi-squared	Hazard ratio	P value
Gender	0.89	1.93	0.35
Presence of cerebellar metastasis	6.74	4.61	0.009*
Number of brain metastases	0.60	0.93	0.44
Presence of adrenal Metastasis	4.89	9.94	0.027*
Craniotomy	4.45	0.27	0.035*
Stereotactic radiosurgery	0.92	0.51	0.34
Treated with whole brain radiation therapy	1.08	2.13	0.298
Treatment with anti-PD-1 antibody	3.68	0.34	0.055

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