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Table 2 Predictors of 10 year breast cancer mortality, Auckland data, 1 Jan 2000–31 Dec 2014

From: Development and validation of a new predictive model for breast cancer survival in New Zealand and comparison to the Nottingham prognostic index

Risk factor

Coefficient

SE

Hazard ratio (HR)

95% confidence limits

p-value

Age under 40

0.085

0.122

1.09

0.86–1.38

0.486

Age (40–49)

−0.003

0.097

1.00

0.83–1.21

0.976

Age (50–59)

  

Ref

  

Age (60–69)

−0.048

0.106

0.95

0.78–1.17

0.652

Age 70 & over

0.388

0.104

1.47

1.20–1.81

< 0.001

Tumour grade 1

  

Ref

  

Tumour grade 2

1.103

0.201

3.01

2.03–4.46

< 0.001

Tumour grade 3

1.504

0.206

4.50

3.01–6.73

< 0.001

Tumour size (0.1–19.9 mm)

  

Ref

  

Tumour size (20–49.9 mm)

0.734

0.088

2.08

1.75–2.48

< 0.001

Tumour size (50 mm & more)

1.047

0.118

2.85

2.26–3.59

< 0.001

Positive lymph nodes (zero node)

  

Ref

  

Positive lymph nodes (1–3 nodes)

0.783

0.094

2.19

1.82–2.63

< 0.001

Positive lymph nodes (4–9 nodes)

1.277

0.106

3.59

2.92–4.41

< 0.001

Positive lymph nodes (10 nodes & more)

1.722

0.111

5.60

4.50–6.96

< 0.001

Presence of metastases at diagnosis

1.603

0.120

4.97

3.93–6.28

< 0.001

No metastases at diagnosis

  

Ref

  

Hormone receptor (1 negative & 1 positive)

0.636

0.096

1.89

1.56–2.28

< 0.001

Hormone receptor (double negative)

1.023

0.091

2.78

2.33–3.32

< 0.001

Hormone receptor (double positive)

  

Ref

  

HER2 status (positive)

−0.206

0.094

0.81

0.68–0.98

< 0.05

HER2 status (test not done)

0.164

0.088

1.18

0.99–1.40

0.061

HER2 status (negative/equivocal)

  

Ref

  

Lobular histological type of cancer

−0.046

0.121

0.95

0.75–1.21

0.702

Other histological type of cancer

−0.576

0.206

0.56

0.38–0.84

< 0.01

Ductal histological type of cancer

  

Ref

  

Maori

0.121

0.121

1.13

0.89–1.43

0.316

Pacific

0.007

0.118

1.01

0.80–1.27

0.949

Other

−0.518

0.124

0.60

0.47–0.76

< 0.001

NZ European

  

Ref

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