Skip to main content

Table 2 Distribution of the genotypes in all participants

From: Genetic variations in PRKAA1 predict the risk and progression of gastric Cancer

Genotype

Controls, n (%)

Patients, n (%)

OR (95% CI)a

p-Value

rs10074991

 AA

128(26.12)

104(21.62)

Reference

 

 AG

261(53.27)

255(53.01)

1.19(0.87,1.62)

0.283

 GG

101(20.61)

122(25.36)

1.44(0.99,2.09)

0.056

 AG/GG

362(73.88)

377(78.38)

1.26(0.94,1.70)

0.127

 Additive model

  

1.21(1.01, 1.46)

0.042

rs13361707

 TT

129(26.33)

103(21.41)

Reference

 

 TC

260(53.06)

256(53.22)

1.22(0.89,1.66)

0.219

 CC

101(20.61)

122(25.36)

1.47(1.01,2.14)

0.043

 TC/CC

361(73.67)

365(75.88)

1.29(0.96,1.74)

0.093

 Addictive model

  

1.22(1.02,1.47)

0.033

rs154268

 TT

297(60.61)

271(56.34)

Reference

 

 TC

176(35.92)

179(37.21)

1.13(0.86,1.47)

0.388

 CC

17(3.47)

31(6.44)

1.96(1.06,3.63)

0.033

 TC/CC

193(39.39)

210(43.66)

1.20(0.93,1.56)

0.158

 Additive model

  

1.24(1.00,1.53)

0.053

rs6882903

 CC

342(69.80)

312(64.86)

Reference

 

 CA

134(27.35)

149(30.98)

0.86(0.41,1.80)

0.687

 AA

14(2.86)

20(4.16)

1.56(0.77,3.15)

0.217

 CA/AA

148(30.20)

169(35.14)

1.26(0.96,1.65)

0.097

 Additive model

  

1.23(0.98,1.55)

0.078

rs3805490

 TT

279(56.94)

280(58.21)

Reference

 

 TA

181(36.94)

170(35.34)

0.93(0.71,1.21)

0.567

 AA

30(6.12)

31(6.44)

1.02(0.60,1.73)

0.953

 TA/AA

211(43.06)

201(41.79)

0.94(0.73,1.21)

0.627

 Additive model

  

0.97(0.79,1.19)

0.756

rs461404

 AA

298(60.82)

270(56.13)

Reference

 

 GA

175(35.71)

179(37.21)

1.14(0.87,1.49)

0.341

 GG

17(3.47)

32(6.65)

2.05(1.11,3.78)

0.022

 GA/GG

192(39.18)

211(43.87)

1.22(0.95,1.58)

0.125

 Additive model

  

1.26(1.01,1.56)

0.037

  1. aAdjusted for age, gender, smoking, drinking, and Helicobacter pylori infection