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Table 2 Multivariable Cox regression for propensity-score matched (PSM) dataset

From: Long-term effects of neoadjuvant radiotherapy, adjuvant radiotherapy, and chemotherapy-only on survival of locally advanced non-small cell lung Cancer undergoing surgery: a propensity-matched analysis

Variable

Cancer-Specific mortality

All-cause mortality

HR (95% CI)

p-value

HR (95% CI)

p-value

Age

1.01 (1.00, 1.02)

0.0027

1.02 (1.01, 1.02)

<.0001

Sex

 Male

Ref.

 

Ref.

 

 Female

0.86 (0.73, 1.02)

0.0781

0.82 (0.70, 0.96)

0.0108

Race

 White

Ref.

 

Ref.

 

 Black

0.88 (0.68, 1.14)

0.3278

0.88 (0.69, 1.11)

0.2748

 Others

0.96 (0.72, 1.27)

0.7764

0.95 (0.73, 1.24)

0.7033

Grade

 I/ II

Ref.

 

Ref.

 

 III/ IV

1.28 (1.07, 1.52)

0.0066

1.26 (1.07, 1.49)

0.0052

 Unknown

0.83 (0.61, 1.11)

0.2023

0.82 (0.62, 1.08)

0.1509

Histology

 Adenocarcinoma

Ref.

 

Ref.

 

 Squamous cell

0.82 (0.67, 1.00)

0.0503

0.85 (0.70, 1.03)

0.0928

 Others

0.88 (0.73, 1.06)

0.1743

0.93 (0.78, 1.11)

0.4148

T classification

 T1

Ref.

 

Ref.

 

 T2

1.27 (1.00, 1.60)

0.0476

1.26 (1.01, 1.56)

0.0375

 T3

1.64 (1.20, 2.24)

0.0020

1.49 (1.11, 2.00)

0.0082

 T4

1.34 (1.01, 1.78)

0.0444

1.24 (0.95, 1.63)

0.1121

N classification

 N0/N1

Ref.

 

Ref.

 

 N2/N3

1.50 (1.17, 1.92)

0.0014

1.38 (1.09, 1.74)

0.0065

Extent of Surgery

 Lobectomy or Bilobectomy

Ref.

 

Ref.

 

 Pneumectomy

1.16 (0.94, 1.43)

0.1593

1.15 (0.95, 1.40)

0.1585

Treatment regimen

 Neoadjuvant RT

Ref.

 

Ref.

 

 Adjuvant RT

1.10 (0.90, 1.35)

0.3689

1.16 (0.96, 1.40)

0.1273

 Surgery + Chemotherapy-Only

1.12 (0.93, 1.35)

0.2382

1.18 (0.99, 1.41)

0.0653

  1. HR Hazard Ratio