Table 1 Clinical and biological variables of 102 subjects with chronic lymphocytic leukemia
From: NDRG2 mRNA levels and miR-28-5p and miR-650 activity in chronic lymphocytic leukemia
Characteristic | Value (%) |
|---|---|
Age | |
  ≤ 60 years | 58 (56.9) |
  > 60 years | 44 (43.1) |
Sex | |
 Male | 69 (67.6) |
 Female | 33 (32.4) |
Binet stage | |
 A | 38 (37.2) |
 B | 33 (32.4) |
 C | 31 (30.4) |
Lymphocytes | |
  < 50 × 109/L | 71 (69.6) |
  ≥ 50 × 109/L | 31 (30.4) |
LDH | |
  ≤ ULN | 79 (77.5) |
  > ULN | 20 (22.5) |
β2-MG | |
  ≤ ULN | 34 (33.3) |
  > ULN | 68 (66.7) |
CD38 (n = 100) | |
  < 30% | 75 (75.0) |
  ≥ 30% | 25 (25.0) |
ZAP-70 (n = 100) | |
  < 20% | 55 (55.0) |
  ≥ 20% | 45 (45.0) |
IGHV (n = 101) | |
 Mutated | 61 (60.4) |
 Unmutated | 40 (39.6) |
p53 aberrations | |
 No TP53 mutation or p53 deletion | 78 (76.4) |
 TP53 mutation or p53 deletion | 24 (23.5) |
del (11q22.3) (n = 93) | |
 Negative | 78 (83.9) |
 Positive | 15 (16.1) |
del (13q14) (n = 65) | |
 Negative | 39 (60.0) |
 Positive | 26 (40.0) |
+ 12 (n = 81) | |
 Negative | 69 (85.2) |
 Positive | 12 (14.8) |