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Table 1 Baseline demographic and tumor characteristics of patients in SEER database

From: Does fibrosis have an impact on survival of patients with hepatocellular carcinoma: evidence from the SEER database?

Variables

Fibrosis Score

P Value

0–4

5–6

Age, years

62.8 ± 11.8

61.0 ± 9.2

< 0.001

Age

<  60

931(40.1)

4457(47.1)

< 0.001

≥ 60

1390(59.9)

5005(52.9)

 

Sex

Male

1804(77.7)

7471(79.0)

0.194

Female

517(22.3)

1991(21.0)

 

Ethnicity

White

1352(58.2)

6709(70.9)

< 0.001

Asian or Pacific Island

621(26.7)

1448(15.3)

 

Black

312(13.5)

1101(11.6)

 

American Indian/Alaska Native

25(1.1)

157(1.7)

 

Unknown

11(0.5)

47(0.5)

 

Marital Status

Married

1298(55.9)

4818(50.9)

< 0.001

Unmarried

932(40.2)

4303(45.5)

 

Unknown

91(3.9)

341(3.6)

 

Year of Diagnosis

2004–2007

670(28.9)

1833(19.4)

< 0.001

2008–2011

864(37.2)

3918(41.4)

 

2012–2014

787(33.9)

3711(39.2)

 

TNM Stage

I

944(40.6)

3520(37.2)

< 0.001

II

437(18.8)

2536(26.8)

 

III

524(22.6)

1840(19.4)

 

IV

280(12.1)

869(9.2)

 

Unknown

136(5.9)

697(7.4)

 

SEER Stage

Localized

1365(58.8)

5366(56.7)

< 0.001

Regional

621(26.7)

3015(31.8)

 

Distant

299(12.9)

910(9.6)

 

Unstaged

36(1.6)

171(1.8)

 

Pathological Grade

Well differentiated

394(17.0)

1055(11.2)

< 0.001

Moderately differentiated

658(28.3)

1484(15.7)

 

Poorly differentiated

279(12.0)

524(5.5)

 

Undifferentiated

22(1.0)

39(0.4)

 

Unknown

968(41.7)

6360(67.2)

 

AFP

Negative

576(24.8)

2116(22.4)

< 0.001

Positive

1324(57.1)

6234(65.9)

 

Borderline

12(0.5)

22(0.2)

 

Unknown

409(17.6)

1090(11.5)

 

Tumor Size

<  2 cm

179(7.7)

1227(13.0)

< 0.001

≥ 2 cm

1918(82.6)

7386(78.0)

 

Unknown

224(9.7)

849(9.0)

 

Therapy

None

1190(51.3)

6536(69.1)

< 0.001

Tumor Destruction

247(10.6)

1251(13.2)

 

Surgical Resection

733(31.6)

639(6.8)

 

Liver Transplantation

137(5.9)

1022(10.8)

 

Unknown

14(0.6)

14(0.1)