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Fig. 8 | BMC Cancer

Fig. 8

From: Novel role of O-glycosyltransferases GALNT3 and B3GNT3 in the self-renewal of pancreatic cancer stem cells

Fig. 8

GALNT3 regulates stemness, clonogenicity and migration in PCSCs. a Tumorsphere sphere formation assay in GALNT3 KO clones compared to control Capan 1 SP cells. b and c Transwell migration and colony formation assay in GALNT3 KO clones compared to control SP cells. d Immunoblotting analysis of CSC markers expression compared to control SP cells. e Schematic representation describing the importance of glycosylation in the maintenance of stemness of PCSCs. Silencing of GALNT3 and B3GNT3 specifically involved in decreasing the self-renewal markers and stemness in PCSCs

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BMC Cancer

ISSN: 1471-2407

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