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Fig. 2 | BMC Cancer

Fig. 2

From: miR-140-5p could suppress tumor proliferation and progression by targeting TGFBRI/SMAD2/3 and IGF-1R/AKT signaling pathways in Wilms’ tumor

Fig. 2

miRNA-140-5p suppresses nephroblastoma cells growth in vitro. Lentivirus containing miRNA-140-5p were transduced into G401 and WT-CLS1 cells, cell proliferation, migratory ability and cell cycle were tested. a The proliferation of G401 and WT-CLS1 cells was downregulated in the miRNA-140-5p group by the CCK8 assay. b The migratory ability of G401 and WT-CLS1 cells were inhibited in the miRNA-140-5p group, representative photographs of cell migration assay were shown. c G401 and WT-CLS1 cells were arrested in the G1/S phase of the cell cycle in the miRNA-140-5p group. *P < 0.05

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