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Table 3 Univariate and multivariate analyses showing significant predictive factors of mortality in the propensity score–matched patients (n = 156)

From: Hepatitis C virus genotype affects survival in patients with hepatocellular carcinoma

Variable

Univariate analysis

Multivariate analysis

P

HR (95% CI)

P

HR (95% CI)

Non-genotype 2

0.007

1.93 (1.19–3.13)

0.004

2.19 (1.29–3.71)

AFP > 200 ng/mL

< 0.001

3.11 (1.86–5.20)

0.001

2.93 (1.55–5.55)

MELD score per point

< 0.001

1.15 (1.08–1.23)

< 0.001

1.23 (1.11–1.37)

Child Pugh class B or C

< 0.001

2.71 (1.66–4.54)

0.287

0.67 (0.31–1.41)

SVR

< 0.001

0.150 (0.06–0.41)

0.002

0.18 (0.06–0.52)

BCLC Stage 0

Reference

Reference

 Stage A

0.235

1.78 (0.69–4.59)

0.021

3.32 (1.20–9.19)

 Stage B

0.001

5.30 (1.97–14.38)

0.001

6.06 (2.08–17.69)

 Stage C

< 0.001

13.16 (4.70–36.87)

< 0.001

18.83 (6.06–58.52)

 Stage D

< 0.001

25.08 (6.45–97.56)

0.004

8.87 (2.02–39.02)

  1. Abbreviation: HR hazard ratio, CI confidence interval, AFP alpha-fetoprotein, SVR sustained virologic response, BCLC Barcelona Clinic Liver Cancer