Fig. 5
From: AXL receptor tyrosine kinase: a possible therapeutic target in acute promyelocytic leukemia
Effect of targeting AXL-RTK on the expression of Wnt/ β-catenin target genes. Cells were cultured in liquid medium (RPMI + 20% FBS + 1% L-Glutamate and 1% Pen/strep) in the presence of 0.01% DMSO and indicated concentrations of R428. Expression analysis was done through qPCR. (A) Expression pattern of AXIN2. (B). Expression pattern of c-myc (C). Expression pattern of HIF1α. (p-values < 0.05 are statistically significant). Bars show mean +/− SD