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Table 3 Operating characteristics for toxicity monitoring

From: PIONEER-Panc: a platform trial for phase II randomized investigations of new and emerging therapies for localized pancreatic cancer

True toxicity probability

Early stopping probability

Average sample size

0.2

0.052

29.2

0.3

0.273

25.8

0.4

0.623

20.1

0.5

0.884

14.9

0.6

0.982

11.8