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  1. Children and adolescents diagnosed with cancer often experience psychological distress, encompassing anxiety, depression, and post-traumatic stress disorder (PTSD). This study aimed to evaluate the prevalence ...

    Authors: Laila S. Al-Saadi, Moon Fai Chan, Amal Al Sabahi, Jalila Alkendi, Nawal Al-Mashaikhi, Hana Al Sumri, Amal Al-Fahdi and Mohammed Al-Azri
    Citation: BMC Cancer 2024 24:518
    Content type: Research Published on:

  2. To effectively embed exercise rehabilitation in cancer survivorship care, a co-ordinated system of acute and community exercise rehabilitation services, forming a stepped model of care, is recommended. Patient...

    Authors: Louise Brennan, Grainne Sheill, Sonya Collier, Peter Browne, Claire L. Donohoe, Linda O’Neill, Juliette Hussey and Emer M. Guinan
    Citation: BMC Cancer 2024 24:517
    Content type: Research Published on:

  3. Numerous studies have indicated that cancer-associated fibroblasts (CAFs) play a crucial role in the progression of colorectal cancer (CRC). However, there are still many unknowns regarding the exact role of C...

    Authors: Shangshang Hu, Qianni Xiao, Rui Gao, Jian Qin, Junjie Nie, Yuhan Chen, Jinwei Lou, Muzi Ding, Yuqin Pan and Shukui Wang
    Citation: BMC Cancer 2024 24:516
    Content type: Research Published on:

  5. Medical consortiums have been extensively established to facilitate the integration of health resources and bridge the technical gap among member institutions. However, some commonly appropriate technologies r...

    Authors: Shiyin Wu, Yuhang Zheng, Lingjie Wang and Wenbin Liu
    Citation: BMC Cancer 2024 24:514
    Content type: Research Published on:

  6. [18F]FDG-PET/CT is used for staging and treatment planning in patients with locally advanced cervical cancer (LACC). We studied if a PET-based prediction model could provide additional risk stratification beyond ...

    Authors: J.A. Adam, E. Poel, B.L.F. van Eck Smit, C.H. Mom, L.J.A. Stalpers, J.J. Laan, E. Kidd, J. Stoker and S. Bipat
    Citation: BMC Cancer 2024 24:513
    Content type: Research Published on:

  8. Although papillary thyroid carcinoma (PTC) has a favorable prognosis, it could affect patient life quality and become a serious threat because of invasion and metastasis. Many investigations have suggested tha...

    Authors: Jiying Shen, Zhirong Ma, Jin Yang, Tianzhen Qu, Yu Xia, Yingjie Xu, Ming Zhou and Weiwei Liu
    Citation: BMC Cancer 2024 24:511
    Content type: Research Published on:

  9. To develop a deep learning(DL) model utilizing ultrasound images, and evaluate its efficacy in distinguishing between benign and malignant parotid tumors (PTs), as well as its practicality in assisting clinici...

    Authors: Tian Jiang, Chen Chen, Yahan Zhou, Shenzhou Cai, Yuqi Yan, Lin Sui, Min Lai, Mei Song, Xi Zhu, Qianmeng Pan, Hui Wang, Xiayi Chen, Kai Wang, Jing Xiong, Liyu Chen and Dong Xu
    Citation: BMC Cancer 2024 24:510
    Content type: Research Published on:

  10. Glioblastoma is a malignant and aggressive type of central nevous system malignancy characterized by many distinct biological features including extensive hypoxia. Hypoxia in glioblatoma associates with comple...

    Authors: Katerina Dvorakova, Veronika Skarkova, Barbora Vitovcova, Jiri Soukup, Hana Vosmikova, Zuzana Pleskacova, Adam Skarka, Michael Christian Bartos, Petr Krupa, Petra Kasparova, Jiri Petera and Emil Rudolf
    Citation: BMC Cancer 2024 24:509
    Content type: Research Published on:

  11. Circulating tumor cell (CTC) clusters play a critical role in carcinoma metastasis. However, the rarity of CTC clusters and the limitations of capture techniques have retarded the research progress. In vitro C...

    Authors: Jueyao Zou, Qiong Chen, Yong He, Yanhong Pan, Han Zhao, Junfeng Shi, Zhonghong Wei, Suyun Yu, Yang Zhao, Xin Han, Yin Lu and Wenxing Chen
    Citation: BMC Cancer 2024 24:507
    Content type: Research Published on:

  12. N1-methyladenosine (m1A), among the most common internal modifications on RNAs, has a crucial role to play in cancer development. The purpose of this study were systematically investigate the modification charact...

    Authors: Yingmin Wu, Lian Li, Long Wang, Shenjie Zhang, Zhirui zeng, Jieyu Lu, Zhi Wang, Yewei Zhang, Shilong Zhang, Haiyang Li and Tengxiang Chen
    Citation: BMC Cancer 2024 24:506
    Content type: Research Published on:

  13. Lung adenocarcinoma is the main type of lung cancer in women. Our previous findings have evidenced that 25-hydroxycholesterol (25-HC) promotes migration and invasion of lung adenocarcinoma cells (LAC), during ...

    Authors: Mengting He, Wenbo Jiang, Xingkai Li, Hongjin Liu, Hongsheng Ren and Yanliang Lin
    Citation: BMC Cancer 2024 24:505
    Content type: Research Published on:

  14. Leptomeningeal metastasis (LM) of small cell lung cancer (SCLC) is a highly detrimental occurrence associated with severe neurological disorders, lacking effective treatment currently. Proteolysis-targeting ch...

    Authors: Min-xing Shi, Xi Ding, Liang Tang, Wei-jun Cao, Bo Su and Jie Zhang
    Citation: BMC Cancer 2024 24:504
    Content type: Research Published on:

  15. The incidence of early-onset colorectal cancer (EOCRC, diagnosed in patients under the age of 50 years) has been increasing around the world. Here, we aimed to systematically identify distinctive features of E...

    Authors: Hongwei Liu, Huifang Xu, Yin Liu, Yuqian Zhao, Xi Zhang, Yanqin Yu, Lingbin Du, Yunyong Liu, Wenjun Wang, Helu Cao, Li Ma, Juanxiu Huang, Ji Cao, Li Li, Yanping Fan, Xiaofen Gu…
    Citation: BMC Cancer 2024 24:503
    Content type: Research Published on:

  16. Paclitaxel is commonly used as a second-line therapy for advanced gastric cancer (AGC). The decision to proceed with second-line chemotherapy and select an appropriate regimen is critical for vulnerable patien...

    Authors: Yonghwa Choi, Jangwoo Lee, Keewon Shin, Ji Won Lee, Ju Won Kim, Soohyeon Lee, Yoon Ji Choi, Kyong Hwa Park and Jwa Hoon Kim
    Citation: BMC Cancer 2024 24:502
    Content type: Research Published on:

  17. For patients with locally advanced rectal cancer (LARC), total neoadjuvant therapy (TNT), namely, intensifying preoperative treatment through the integration of radiotherapy and systemic chemotherapy before su...

    Authors: Tongzhen Xu, Lingling Feng, Wenjue Zhang, Haoyue Li, Huiying Ma, Muyasha Abulimiti, Yutong Tan, Feiyan Deng, Wenting Huang, Shuangmei Zou, Wenyan Kang, Liming Jiang, Ying Wang, Chen Hu, Yinggang Chen, Haitao Zhou…
    Citation: BMC Cancer 2024 24:501
    Content type: Study Protocol Published on:

  18. Our aim was to develop a validated Patient Reported Experience Measure (PREM) to capture patient and carer experience during participation in experimental cancer medicine trials (ECM): called PREM-ECM.

    Authors: Chelsea S. Sawyer, Sally Taylor, Louise Carter, Melissa Stanworth, Michelle Davies, Fiona Thistlethwaite, Jo Taylor, Charlotte Eastwood and Janelle Yorke
    Citation: BMC Cancer 2024 24:500
    Content type: Research Published on:

  19. Germline mutations in BRCA1 and BRCA2 genes are among the main causes of hereditary ovarian cancer. Identifying these mutations may reduce cancer risk, facilitate early detection, and enable personalized treat...

    Authors: Caroline de Oliveira Ferreira, Vandré Cabral Gomes Carneiro and Carolline Araujo Mariz
    Citation: BMC Cancer 2024 24:499
    Content type: Research Published on:

  20. Lack of agreed terminology and definitions in healthcare compromises communication, patient safety, optimal management of adverse events, and research progress. The purpose of this scoping review was to unders...

    Authors: Kerrie Curtis, Karla Gough, Meinir Krishnasamy, Elena Tarasenko, Geoff Hill and Samantha Keogh
    Citation: BMC Cancer 2024 24:498
    Content type: Research Published on:

  22. Ferroptosis has important value in cancer treatment. It is significant to explore the new ferroptosis-related lncRNAs prediction model in Hepatocellular carcinoma (HCC) and the potential molecular mechanism of...

    Authors: Ke Zong, Caifeng Lin, Kai Luo, Yilei Deng, Hongfei Wang, Jianfei Hu, Shi Chen and Renfeng Li
    Citation: BMC Cancer 2024 24:496
    Content type: Research Published on:

  23. Although many studies have explored the correlation between quality of life and survival, none have reported this relationship for specific cancers assessed at distinct time points. This meta-analysis aimed to...

    Authors: Taro Okayama, Katsuyoshi Suzuki, Shinichiro Morishita, Junichiro Inoue, Takashi Tanaka, Jiro Nakano and Takuya Fukushima
    Citation: BMC Cancer 2024 24:495
    Content type: Systematic Review Published on:

  24. Informal caregivers (ICs) of patients with cancer provide essential and mainly uncompensated care. A self-perceived preparedness to care for the patient is associated with a lower caregiver burden, described a...

    Authors: Birgitta Johansson, Åsa Cajander, Awais Ahmad, Emma Ohlsson-Nevo, Per Fransson, Brith Granström, Louise von Essen, Ulrica Langegård, Mona Pettersson, Anna Henriksson and Ylva Tiblom Ehrsson
    Citation: BMC Cancer 2024 24:494
    Content type: Study Protocol Published on:

  25. Muscle mass is important for metastatic prostate cancer survival and quality of life (QoL). The backbone of treatment for men with metastatic castration sensitive prostate cancer (mCSPC) is androgen deprivatio...

    Authors: Adriana M Coletta, Lea Haverbeck Simon, Kelsey Maslana, Sarah Taylor, Kish Larson, Pamela A Hansen, Vinay Mathew Thomas, Cornelia M Ulrich, Manish Kohli, Jonathan Chipman, Umang Swami, Sumati Gupta, Benjamin L Maughan and Neeraj Agarwal
    Citation: BMC Cancer 2024 24:493
    Content type: Study Protocol Published on:

  27. This study aimed to systematically analyze the effect of a serine/threonine kinase (STK11) mutation (STK11mut) on therapeutic efficacy and prognosis in patients with non-small cell lung cancer (NSCLC).

    Authors: Ke Xu, Weinan Lu, Airu Yu, Hongwei Wu and Jie He
    Citation: BMC Cancer 2024 24:491
    Content type: Research Published on:

  28. Patients with rheumatologic preexisting autoimmune disease (PAD) have not been enrolled in clinical trials of immune checkpoint inhibitors (ICIs). Therefore, the risks and benefits of ICI therapy in such patie...

    Authors: Xin Liu, Su Li, Liyuan Ke and Hongxia Cui
    Citation: BMC Cancer 2024 24:490
    Content type: Systematic Review Published on:

  29. Next-generation sequencing (NGS) is essential for lung cancer treatment. It is important to collect sufficient tissue specimens, but sometimes we cannot obtain large enough samples for NGS analysis. We investi...

    Authors: Chihiro Mimura, Rei Takamiya, Shodai Fujimoto, Takafumi Fukui, Atsuhiko Yatani, Jun Yamada, Mizuki Takayasu, Naoya Takata, Hiroki Sato, Kiyoko Fukuda, Koichi Furukawa, Daisuke Hazama, Naoko Katsurada, Masatsugu Yamamoto, Shingo Matsumoto, Koichi Goto…
    Citation: BMC Cancer 2024 24:489
    Content type: Research Published on:

  30. Meningiomas are among the most common primary tumors of the central nervous system. Previous research into the meningioma histological appearance, genetic markers, transcriptome and epigenetic landscape has re...

    Authors: D. Orešković, A. Madero Pohlen, I. Cvitković, J.F. Alen, M. Raguž, A. Álvarez-Sala de la Cuadra, G.J. Bazarra Castro, Z. Bušić, I. Konstantinović, V. Ledenko, C. Martínez Macho, D. Müller, M. Žarak, N. Jovanov-Milosevic, D. Chudy and T. Marinović
    Citation: BMC Cancer 2024 24:488
    Content type: Research Published on:

  31. Authors: Alessio Cirillo, Daniele Marinelli, Umberto Romeo, Daniela Messineo, Francesca De Felice, Marco De Vincentiis, Valentino Valentini, Silvia Mezi, Filippo Valentini, Luca Vivona, Antonella Chiavassa, Bruna Cerbelli, Daniele Santini, Paolo Bossi, Antonella Polimeni, Paolo Marchetti…
    Citation: BMC Cancer 2024 24:487
    Content type: Correction Published on:

    The original article was published in BMC Cancer 2024 24:430

  32. The antiviral drug Nirmatrelvir was found to be a key drug in controlling the progression of pneumonia during the infectious phase of COVID-19. However, there are very few options for effective treatment for c...

    Authors: Xiaoyan Yin, Wanqi Zhu, Xiaoyong Tang, Guangjian Yang, Xianguang Zhao, Kaikai Zhao, Liyang Jiang, Xiaolin Li, Hong Zhao, Xin Wang, Yuanyuan Yan, Ligang Xing, Jinming Yu, Xiangjiao Meng and Hanxi Zhao
    Citation: BMC Cancer 2024 24:486
    Content type: Research Published on:

  33. Patients-derived xenograft (PDX) model have been widely used for tumor biological and pathological studies. However, the metabolic similarity of PDX tumor to the primary cancer (PC) is still unknown.

    Authors: Shi Wen, Xianchao Lin, Wei Luo, Yu Pan, Fei Liao, Zhenzhao Wang, Bohan Zhan, Jianghua Feng and Heguang Huang
    Citation: BMC Cancer 2024 24:485
    Content type: Research Published on:

  34. This article examines the potential of using liquid biopsy with piRNAs to study cancer survival outcomes. While previous studies have explored the relationship between piRNA expression and cancer patient outco...

    Authors: Mohammad Taghizadeh, Tohid Jafari-Koshki, Vahid Jafarlou, Mortaza Raeisi, Leila Alizadeh, Yousef Roosta, Somaieh Matin, Rahele Jabari, Daniel Sur and Abbas Karimi
    Citation: BMC Cancer 2024 24:484
    Content type: Systematic Review Published on:

  35. To compare the clinical characteristics and prognoses of patients with isolated regional lymph node recurrent nasopharyngeal carcinoma (irrNPC) who underwent surgery or re-irradiation treatment.

    Authors: Yuebing Chen, Yiping Huang, Xiaoqiang Chen, Zhiwei Chen, Xiane Peng, Shaojun Lin, Cheng Lin and Jingfeng Zong
    Citation: BMC Cancer 2024 24:483
    Content type: Research Published on:

  36. Therapies for metastatic castration-resistant prostate cancer (mCRPC) include targeting the androgen receptor (AR) with androgen receptor inhibitors (ARIs) and prostate-specific membrane antigen (PSMA). Having...

    Authors: Haiyan E. Liu, Meghah Vuppalapaty, Christian R. Hoerner, Colin P. Bergstrom, Michael Chiu, Clementine Lemaire, James Che, Amanpreet Kaur, Adam Dimmick, Sean Liu, Thomas J. Metzner, Menna Araya, Steve Crouse, Markus Sprenger-Haussels, Martin Schlumpberger, John T. Leppert…
    Citation: BMC Cancer 2024 24:482
    Content type: Research Published on:

  37. The treatment for lung oligometastasis from colorectal cancer (CRC) remains challenging. This retrospective study aimed to compare the local tumor control, survival and procedure-related complications in CRC p...

    Authors: Yuliang Li, Zitong Chen, Shuhui Tian, Xujian Han, Changjun Wang, Yongzheng Wang and Bin Liu
    Citation: BMC Cancer 2024 24:481
    Content type: Research Published on:

  38. The treatment of hepatocellular carcinoma (HCC) patients exhibiting high-risk characteristics (Vp4, and/or bile duct invasion, and/or tumor occupancy ≥ 50%) lacks standardized approaches and yields unfavorable...

    Authors: Xu Chang, Xinge Li, Peng Sun, Zhenfeng Li, Pengfei Sun and Shangkun Ning
    Citation: BMC Cancer 2024 24:480
    Content type: Research Published on:

  39. Rectal cancer treatment has transformed in recent years, with neoadjuvant treatment (NT) and total neoadjuvant treatment (TNT) aiming to enhance pathological responses. This pioneering study in our country del...

    Authors: Misbah Younus Soomro, Saqib Raza Khan, Hafiz Muhammad, Sujjawal Ahmad, Nawazish Zehra, Insia Ali, Mirza Rameez Samar, Arif Hameed, Munira Moosajee and Yasmin Abdul Rashid
    Citation: BMC Cancer 2024 24:479
    Content type: Research Published on:

  40. Anxiety is a prevalent comorbidity in lung cancer (LC) patients associated with a decline in quality of life. Dehydroepiandrosterone (DHEA), a neuroactive steroid, levels rise in response to stress. Prior rese...

    Authors: Jia-Rong Wu, Vincent Chin -Hung Chen, Yu-Hung Fang, Ching-Chuan Hsieh and Shu-I Wu
    Citation: BMC Cancer 2024 24:476
    Content type: Research Published on:

  41. Underlying liver disease is correlated with hepatocellular carcinoma (HCC) development in patients with hepatitis B virus (HBV) infection. However, the impact of hepatic inflammation and fibrosis on the patien...

    Authors: Xiangyong Hao, Liangliang Xu, Xiang Lan, Bo Li and Hui Cai
    Citation: BMC Cancer 2024 24:475
    Content type: Research Published on:

  46. To assess the diagnostic performance of a panel of standard tumor markers (TMs) in patients hospitalized with significant involuntary weight loss (IWL) and elevated levels of inflammation biomarkers, and a com...

    Authors: Morgane Gronnier, Kaies Hedhli, Chloé Sauzay, Valéry Salle, Pierre Duhaut, Jean Schmidt and Amandine Dernoncourt
    Citation: BMC Cancer 2024 24:468
    Content type: Research Published on:

  47. The incidence of thyroid cancer as the most common type of endocrine gland malignancy has risen more significantly than any malignancies in recent years. Estimated new cases of thyroid cancer in the United Sta...

    Authors: Zahra Maleki, Jafar Hassanzadeh and Haleh Ghaem
    Citation: BMC Cancer 2024 24:467
    Content type: Research Published on:

  48. [18 F]-Fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) has the ability to detect local and/or regional recurrence as well as distant metastasis. We aimed to evaluate the prog...

    Authors: Zhe Dong, Gao-Yuan Wang, Dong-Yu Dai, Guan-Jie Qin, Ling-Long Tang, Cheng Xu and Jun Ma
    Citation: BMC Cancer 2024 24:466
    Content type: Research Published on:

  49. Gastric cancer (GC) lacks serum biomarkers with clinical diagnostic value. Multi-omics analysis is an important approach to discovering cancer biomarkers. This study aimed to identify and validate serum biomar...

    Authors: Shao-Song Liu, Qin-Si Wan, Cong Lv, Jin-Ke Wang, Song Jiang, Dan Cai, Mao-Sheng Liu, Ting Wang and Kun-He Zhang
    Citation: BMC Cancer 2024 24:465
    Content type: Research Published on:

  50. In this study, we retrospectively investigated the prognostic role of pre-treatment neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) in esophageal squamous cell carcinoma patients (E...

    Authors: Qirong Man, Peishun Li, Jing Fan, Sen Yang, Chao Xing, Yunling Bai, Miaomiao Hu, Baohu wang and Kaixian Zhang
    Citation: BMC Cancer 2024 24:464
    Content type: Research Published on:

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