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  1. Resveratrol has demonstrated its ability to regulate BRCA1 gene expression in breast cancer cells, and previous studies have established the binding of MBD proteins to BRCA1 gene promoter regions. However, the mo...

    Authors: Ram Krishna Sahu, Simran Tandon, Shalini Singh, Bhudev Chandra Das and Suresh T Hedau
    Citation: BMC Cancer 2024 24:566
    Content type: Research Published on:

  2. Recent studies showed heterogeneity in stage IVB patients. However, few studies focused on the prognosis of supraclavicular metastatic ovarian cancer. This study aimed to explore the prognostic factors and the...

    Authors: Chenlian Quan, Xiaojun Chen, Hao Wen, Xiaohua Wu and Jin Li
    Citation: BMC Cancer 2024 24:565
    Content type: Research Published on:

  3. 5-Fluorouracil (5FU) is a primary chemotherapeutic agent used to treat oral squamous cell carcinoma (OSCC). However, the development of drug resistance has significantly limited its clinical application. There...

    Authors: Xuyang Zhang, Kairui Sun, Ruihuan Gan, Yuxiang Yan, Chaochao Zhang, Dali Zheng and Youguang Lu
    Citation: BMC Cancer 2024 24:564
    Content type: Research Published on:

  4. Authors: Monica Niger, Federico Nichetti, Lorenzo Fornaro, Chiara Pircher, Federica Morano, Federica Palermo, Lorenza Rimassa, Tiziana Pressiani, Rossana Berardi, Andrea Casadei Gardini, Elisa Sperti, Lisa Salvatore, Davide Melisi, Francesca Bergamo, Salvatore Siena, Stefania Mosconi…
    Citation: BMC Cancer 2024 24:563
    Content type: Correction Published on:

    The original article was published in BMC Cancer 2024 24:436

  6. Modulation of DNA damage repair in lung squamous cell carcinoma (LUSC) can result in the generation of neoantigens and heightened immunogenicity. Therefore, understanding DNA damage repair mechanisms holds sig...

    Authors: Lu Xia, Hexin Lin, Huifen Cao and Jiabian Lian
    Citation: BMC Cancer 2024 24:561
    Content type: Research Published on:

  7. Developing countries have a significantly higher incidence of breast cancer in patients younger than 40 years as compared to developed countries. This study aimed to examine if young age at diagnosis is an ind...

    Authors: Eman Sbaity, Hani Tamim, Ghada El-Hajj Fuleihan, Jaber Abbas, Mariam Zahwe, Razan El Sayed and Ali Shamseddine
    Citation: BMC Cancer 2024 24:560
    Content type: Research Published on:

  8. In contrast to the decreasing trends in developed countries, the incidence and mortality rates of cervical squamous cell carcinoma in China have increased significantly. The screening and identification of rel...

    Authors: Aiqin Zhao, Yunzhi Pan, Yingyin Gao, Zheng Zhi, Haiying Lu, Bei Dong, Xuan Zhang, Meiying Wu, Fenxia Zhu, Sufang Zhou and Sai Ma
    Citation: BMC Cancer 2024 24:559
    Content type: Research Published on:

  9. Portal hypertension (PHT) has been proven to be closely related to the development of hepatocellular carcinoma (HCC). Whether PHT before liver transplantation (LT) will affect the recurrence of HCC is not clear.

    Authors: Guo Wei, Yong Zhao, Shifeng Feng, Jingsheng Yuan, Gang Xu, Tao Lv, Jian Yang, Lingxiang Kong and Jiayin Yang
    Citation: BMC Cancer 2024 24:558
    Content type: Research Published on:

  10. While radiation therapy remains pivotal in esophageal squamous cell carcinoma (ESCC) treatment, the perplexing phenomenon of post-radiation metastasis presents a formidable clinical challenge. This study inves...

    Authors: Shan Huang, Jiayi Zhang, Pu He, Xinyue Cui, Yuzhu Hou, Wanghui Su and Fang Li
    Citation: BMC Cancer 2024 24:557
    Content type: Research Published on:

  11. Radiotherapy is a mainstay of cancer treatment. The clinical response to radiotherapy is heterogeneous, from a complete response to early progression. Recent studies have explored the importance of patient cha...

    Authors: Venkata SK. Manem and Farzad Taghizadeh-Hesary
    Citation: BMC Cancer 2024 24:556
    Content type: Editorial Published on:

  12. Periampullary cancers, including pancreatic ductal adenocarcinoma, ampullary-, cholangio-, and duodenal carcinoma, are frequently diagnosed in an advanced stage and are associated with poor overall survival. T...

    Authors: Stina Margrethe Stålberg, Laxmi Silwal-Pandit, Nasser Ezzatkhah Bastani, Daniel Johan Hammer Nebdal, Ole Christian Lingjærde, Bjørn Steen Skålhegg and Elin Hegland Kure
    Citation: BMC Cancer 2024 24:555
    Content type: Research Published on:

  13. Prostate cancer is dependent on androgen receptor (AR) signaling, and androgen deprivation therapy (ADT) has proven effective in targeting prostate cancer. However, castration-resistant prostate cancer (CRPC) ...

    Authors: Daisuke Obinata, Kenichi Takayama, Mitchell G Lawrence, Daigo Funakoshi, Makoto Hara, Birunthi Niranjan, Linda Teng, Renea A Taylor, Gail P Risbridger, Satoru Takahashi and Satoshi Inoue
    Citation: BMC Cancer 2024 24:554
    Content type: Research Published on:

  14. Cancer incidence is increasing in Ethiopia mainly due to increased life expectancy, while oncological capacities remain limited. Strong referral linkages between different levels of the healthcare system are k...

    Authors: Josephin Trabitzsch, Morena Marquardt, Sarah Negash, Winini Belay, Yonas Abebe, Edom Seife, Kunuz Abdella, Muluken Gizaw, Sefonias Getachew, Adamu Addissie, Eva Johanna Kantelhardt and Abigiya Wondimagegnehu
    Citation: BMC Cancer 2024 24:553
    Content type: Research Published on:

  17. Long nonconding RNAs (lncRNAs) have been found to be a vital regulatory factor in the development process of human cancer, and could regarded as diagnostic or prognostic biomarkers for human cancers. Here, we ...

    Authors: Shiping Huang, Zhouxiang Liao, Xiao He, Zhenyu Song, Xi Fang, Sha Wen, Lichao Yang, Hui Li, Qi Zhang, Wanling Mo, Xiaojing Cheng, Min He and Xuejing Huang
    Citation: BMC Cancer 2024 24:550
    Content type: Research Published on:

  18. Accurate assessment of axillary status after neoadjuvant therapy for breast cancer patients with axillary lymph node metastasis is important for the selection of appropriate subsequent axillary treatment decis...

    Authors: Jia Wang, Cong Tian, Bing-Jie Zheng, Jiao Zhang, De-Chuang Jiao, Jin-Rong Qu and Zhen-Zhen Liu
    Citation: BMC Cancer 2024 24:549
    Content type: Research Published on:

  19. For patients with early-stage cervical cancer without high-risk factors, there is no consensus regarding the optimal postoperative treatment regimen and whether postoperative concurrent radiochemotherapy (CCRT...

    Authors: Yuncan Zhou, Weiping Wang, Jia Tang, Ke Hu and Fuquan Zhang
    Citation: BMC Cancer 2024 24:548
    Content type: Research Published on:

  20. The purpose of this study was to develop an individual survival prediction model based on multiple machine learning (ML) algorithms to predict survival probability for remnant gastric cancer (RGC).

    Authors: Zhouwei Zhan, Bijuan Chen, Hui Cheng, Shaohua Xu, Chunping Huang, Sijing Zhou, Haiting Chen, Xuanping Lin, Ruyu Lin, Wanting Huang, Xiaohuan Ma, Yu Fu, Zhipeng Chen, Hanchen Zheng, Songchang Shi, Zengqing Guo…
    Citation: BMC Cancer 2024 24:547
    Content type: Research Published on:

  21. Cancer survival and mortality outcomes for people with mental health and substance use conditions (MHSUC) are worse than for people without MHSUC, which may be partly explained by poorer access to timely and a...

    Authors: Ruth Cunningham, James Stanley, Fiona Imlach, Tracy Haitana, Helen Lockett, Susanna Every-Palmer, Mau Te Rangimarie Clark, Cameron Lacey, Kendra Telfer and Debbie Peterson
    Citation: BMC Cancer 2024 24:546
    Content type: Research Published on:

  22. Cancer survivors have a high risk of mortality, and vitamin D (VD) is associated with the risk of mortality. This study is aim to examine the impact of VD on mortality in cancer survivors.

    Authors: Xiaofei Mo, Chen He, Fengfeng Han, Hui Yan, Xueqin Chen, Yuetao Wang and Mingge Zhou
    Citation: BMC Cancer 2024 24:545
    Content type: Research Published on:

  24. This study aimed to evaluate the prognostic significance of postoperative Creatine Kinase type M and B (CK-MB) to total Creatine Kinase (CK) ratio (CK-MB/CK) in colorectal cancer (CRC) patients after radical r...

    Authors: Lubei Rao, Pingyao Xu, Guiji Zhang, Ruiling Zu, Yajun Luo, Kaijiong Zhang, Ying Yang, Dongsheng Wang, Shuya He, Huaichao Luo and Bo Ye
    Citation: BMC Cancer 2024 24:543
    Content type: Research Published on:

  26. The goal of the research was to assess the quantitative relationship between median progression-free survival (PFS) and median overall survival (OS) specifically among patients with relapsed/refractory multipl...

    Authors: Meletios Dimopoulos, Pieter Sonneveld, Salomon Manier, Annette Lam, Tito Roccia, Jordan M. Schecter, Patricia Cost, Lida Pacaud, Abbey Poirier, Gabriel Tremblay, Tommy Lan, Satish Valluri and Shaji Kumar
    Citation: BMC Cancer 2024 24:541
    Content type: Research Published on:

  28. There is no updated national data regarding the real impact of the COVID-19 pandemic on delaying diagnosis and treatment among patients with lung, and head, and neck cancers in Brazil. This study aimed to anal...

    Authors: Gilson Gabriel Viana Veloso, Flávia Duarte Amaral and Angélica Nogueira-Rodrigues
    Citation: BMC Cancer 2024 24:539
    Content type: Research Published on:

  29. Patients with immunocompromise were suspected to encounter a high risk for severe coronavirus disease 2019 (COVID-19) infection on early period; however, data is lacking nowadays and immune response remain unc...

    Authors: Na Zhang, Zhen Wang, Hong Li, Kai Chen, Hong-sheng Wang, Jing-bo Shao, Sha-yi Jiang, Xiao-wen Zhai and Hui Jiang
    Citation: BMC Cancer 2024 24:538
    Content type: Research Published on:

  30. The tripartite motif (TRIM) proteins have been reported to play crucial roles in various malignancies. However, the clinical significance of TRIM proteins in colorectal cancer (CRC) remains controversial. This...

    Authors: Ying Wu, Chen Chen, Xian Hua, Chunhua Zhao and Han Min
    Citation: BMC Cancer 2024 24:537
    Content type: Research Published on:

  31. Cervical lymph node metastasis (LNM) is an important prognostic factor for patients with non-small cell lung cancer (NSCLC). We aimed to develop and validate machine learning models that use ultrasound radiomi...

    Authors: Zhiqiang Deng, Xiaoling Liu, Renmei Wu, Haoji Yan, Lingyun Gou, Wenlong Hu, Jiaxin Wan, Chenwanqiu Song, Jing Chen, Daiyuan Ma, Haining Zhou and Dong Tian
    Citation: BMC Cancer 2024 24:536
    Content type: Research Published on:

  32. Immunotherapy based on the application of immune checkpoint inhibitors (ICIs) is one of the standard treatments for advanced non-small cell lung cancer (NSCLC). Non-alcoholic fatty liver Disease (NAFLD) has de...

    Authors: Yi Li, Bingxin Gong, Yusheng Guo, Weiwei Liu, Chao Chen, Shanshan Jiang, Feng Pan, Jiyu Song, Lian Yang and Guofeng Zhou
    Citation: BMC Cancer 2024 24:535
    Content type: Research Published on:

  33. While there is an understanding of the association between the expression of Porphyromonas gingivalis (P. gingivalis) and prognosis of oral squamous cell carcinoma (OSCC), significance specially to address the re...

    Authors: Chenxi Li, Muqiu Li, Wei Wei, Zhengye Wang, Jingwen Yu and Zhongcheng Gong
    Citation: BMC Cancer 2024 24:534
    Content type: Research Published on:

  34. In Saudi Arabia, approximately one-third of colorectal cancer (CRC) patients are diagnosed at an advanced stage. Late diagnosis is often associated with a worse prognosis. Understanding the risk factors for la...

    Authors: Norah Alsadhan, Sultana A Alhurishi, Mar Pujades-Rodriguez, Farag Shuweihdi, Cathy Brennan and Robert M West
    Citation: BMC Cancer 2024 24:533
    Content type: Research Published on:

  35. Aberrant expressions of desmoglein 2 (Dsg2) and desmocollin 2(Dsc2), the two most widely distributed desmosomal cadherins, have been found to play various roles in cancer in a context-dependent manner. Their s...

    Authors: Ji-Yuan Han, Na Che, Jing Mo, Dan-Fang Zhang, Xiao-Hui Liang, Xue-Yi Dong, Xiu-Lan Zhao and Bao-Cun Sun
    Citation: BMC Cancer 2024 24:532
    Content type: Research Published on:

  36. In the pathogenesis of myeloproliferative neoplasms (MPN), inflammation plays an important role. However, it is unclear whether there is a causal link between inflammation and MPNs. We used a bidirectional, tw...

    Authors: Hao Xiong, Huitao Zhang, Jun Bai, Yanhong Li, Lijuan Li and Liansheng Zhang
    Citation: BMC Cancer 2024 24:531
    Content type: Research Published on:

  37. In low-income countries there is insufficient evidence on hematological, clinical, cytogenetic and molecular profiles among new CML patients. Therefore, we performed this study among newly confirmed CML patien...

    Authors: Fekadu Urgessa, Boki Lengiso, Aster Tsegaye, Amha Gebremedhin, Fozia Abdella, Fisihatsion Tadesse, Jerald Radich, Helen Nigussie and Teklu Kuru Gerbaba
    Citation: BMC Cancer 2024 24:530
    Content type: Research Published on:

  40. Tumor Treating Fields (TTFields) Therapy is an FDA-approved therapy in the first line and recurrent setting for glioblastoma. Despite Phase 3 evidence showing improved survival with TTFields, it is not uniform...

    Authors: Priya Kumthekar, Madison Lyleroehr, Leilani Lacson, Rimas V. Lukas, Karan Dixit, Roger Stupp, Timothy Kruser, Jeff Raizer, Alexander Hou, Sean Sachdev, Margaret Schwartz, Jessica Bajas PA, Ray Lezon, Karyn Schmidt, Christina Amidei and Karen Kaiser
    Citation: BMC Cancer 2024 24:527
    Content type: Research Published on:

  41. Panel gene sequencing is an established diagnostic tool for precision oncology of solid tumors, but its utility for the treatment of cancers of the digestive system in clinical routine is less well documented.

    Authors: Lena Dreikhausen, Anna Klupsch, Isabella Wiest, Qiyun Xiao, Nadine Schulte, Johannes Betge, Tobias Boch, Christoph Brochhausen, Timo Gaiser, Ralf-Dieter Hofheinz, Matthias Ebert and Tianzuo Zhan
    Citation: BMC Cancer 2024 24:526
    Content type: Research Published on:

  43. Nutritional impact symptoms (NISs) are proposed to be a key indicator of decreased dietary intake in patients with solid cancer. Cancer patients frequently experience NIS from the disease itself and from disea...

    Authors: Muna H. Shakhshir, Husam T. Salameh, Riad Amer and Sa’ed H. Zyoud
    Citation: BMC Cancer 2024 24:524
    Content type: Research Published on:

  44. Although numerous studies have reported the prognostic value of the lung immune prognostic index (LIPI) in non-small cell lung cancer (NSCLC) patients treated with immune checkpoint inhibitors (ICIs), the prog...

    Authors: Yusheng Guo, Yao Pan, Jiayu Wan, Bingxin Gong, Yi Li, Xuefeng Kan and Chuansheng Zheng
    Citation: BMC Cancer 2024 24:523
    Content type: Systematic Review Published on:

  45. Metastatic disease is a major and difficult-to-treat complication of lung cancer. Considering insufficient effectiveness of existing therapies and taking into account the current problem of lung cancer chemore...

    Authors: E. Skurikhin, N. Ermakova, M. Zhukova, E. Pan, D. Widera, L. Sandrikina, L. Kogai, O. Pershina, A. Pakhomova, V. Yu. Pan, N. Kushlinskii, A. Kubatiev, S. Morozov and A. Dygai
    Citation: BMC Cancer 2024 24:522
    Content type: Research Published on:

  46. Emerging evidence suggests that the gut microbiota is associated with various intracranial neoplastic diseases. It has been observed that alterations in the gut microbiota are present in gliomas, meningiomas, ...

    Authors: Chunhui Liu, Fangzheng Liu, Ding Nie, Youchao Xiao, Wentao Wu, Yanfei Jia, Lu Jin, Ning Qiao, Kefan Cai, Siming Ru, Xin Liu, Yifan Song, Jintian Xu, Lei Cao and Songbai Gui
    Citation: BMC Cancer 2024 24:521
    Content type: Research Published on:

  47. Acute myeloid leukaemia (AML) is a fatal haematopoietic malignancy and is treated with the conventional combination of cytarabine (Ara-C) and daunorubicin (Dau). The survival rate of AML patients is lower due ...

    Authors: Yang Qiu, Lu Bai, Haosen Zhao and Xifan Mei
    Citation: BMC Cancer 2024 24:520
    Content type: Research Published on:

  48. Uveal melanoma (UVM) is the most common primary intraocular tumor in adults, with a median survival of 4–5 months following metastasis. DNA damage response (DDR) upregulation in UVM, which could be linked to i...

    Authors: Yingxu Zhang, Jinbiao Zheng, Minyu Chen, Shulun Zhao, Ruiqian Ma, Wenwei Chen and Jiahui Liu
    Citation: BMC Cancer 2024 24:519
    Content type: Research Published on:

  50. Although papillary thyroid carcinoma (PTC) has a favorable prognosis, it could affect patient life quality and become a serious threat because of invasion and metastasis. Many investigations have suggested tha...

    Authors: Jiying Shen, Zhirong Ma, Jin Yang, Tianzhen Qu, Yu Xia, Yingjie Xu, Ming Zhou and Weiwei Liu
    Citation: BMC Cancer 2024 24:511
    Content type: Research Published on:

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