Fig. 7

The effect of cell therapy naive and reprogrammed CD8⁺ T-cells on cancer cells and cancer stem cells (CSCs). A The number of Axl⁺, CD117⁺CD44⁺, CD117⁺EGF⁺, and CD117⁺EGF⁺CD44⁺ cells in lung mice with LLC, d10 (% of total mononuclear cells number); B relative number of Sox2⁺ cells in a population of Axl⁺, CD117⁺CD44⁺, CD117⁺EGF⁺, and CD117⁺EGF⁺CD44⁺ cells (% of stained CSCs). *– for comparison with intact control, ●– for comparison with LLC, +– for comparison with naive T-cells (Mann–Whitney test, p-value < 0.05). All data were obtained using flow cytometry