CSCs populations | T-cells populations/Characteristic |
---|---|
Axl+ | CD8+CD45RA+CD197hiCD62L+CD95+ / Stem cell–like memory (TSCM) CD8+ T cells. This population have high self-renewability, multipotency and proliferation capacity |
Axl+Sox2+ | CD3+CD4+CD8−Ki67+ / Proliferating CD4+T-cells |
Axl+CD117+ | CD3+CD4+Ki67+PD-1+ / Activated proliferating CD4+T-cells |
CD44hiCD90+Sox2+ | CD3+CD8+Ki67+PD-1+ / Activated proliferating CD8+T-cells |
CD117+CD44+ | CD3+CD8+Ki67+ / Proliferating CD8+T-cells |
CD117+EGF+CD44+PD-L1+PD-1+ | CD3+CD8+PD-1+ / Exhausted CD8+ T-cells. This population is characterized by decreased antigen-dependent cytokine secretion and increased expression of inhibitory surface receptors |
CD117+Sox2+ | CD4−CD3−CD8+CD62L+ / Memory CD8+T-cells |
CD117+EGF+ | Â |
CD117+EGF+CD44+ | Â |
EGF+CD44+Sox2+ | Â |
CD117+EGF+CD44+Sox2+ | Â |