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Fig. 1 | BMC Cancer

Fig. 1

From: Desmoglein 2 and desmocollin 2 depletions promote malignancy through distinct mechanisms in triple-negative and luminal breast cancer

Fig. 1

The low mRNA expressions of Dsg2 and Dsc2 were associated with progressionand poor prognosis by bioinformatics analysis. (A-D) The mRNA expressions of Dsg2 and Dsc2 were reduced in BC tissues from TCGA database (A, C) and TNMplot database (B, D). (E-F) The mRNA expressions of Dsg2 and Dsc2 were associated with molecular subtypes of BC from TCGA database. (G-J) The mRNA expression levels of Dsg2 and Dsc2 were negatively correlated with stage and nodal metastasis status of BC from TCGA database. (K-V) KM plotter analysis showed the low mRNA expressions of Dsg2 and Dsc2 were associated with poor overall survival whatever in all population or in molecular subtypes. (W-X) The mRNA expressions of Dsg2 and Dsc2 were positively correlated in normal breast tissues (W) and in BC tissues from the TNMplot data. *indicates P < 0.05

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BMC Cancer

ISSN: 1471-2407

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