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  1. Meningioma, the most prevalent intracranial tumor, possesses a significant propensity for malignant transformation. Circular RNAs (circ-RNAs), a class of non-coding RNAs, have emerged as crucial players in tum...

    Authors: Yongkai Huang, Zhihui Wu, Zewei Peng, Anmin Liu, Wen Yuan, Deqing Han and Junmin Peng
    Citation: BMC Cancer 2024 24:345
  2. To establish a nomogram to predict the probability of survival of patients with stage II/III gastric cancer (GC) who received incomplete peri-operative adjuvant chemotherapy (PAC).

    Authors: Dian Liu, Hu Quan, Min Ma, Huijun Zhou, Xiaolin Yang, Zhengchun Wu, Jia Luo, Hua Xiao and Yanping Xiao
    Citation: BMC Cancer 2024 24:344
  3. Regular Low-Dose Computed Tomography (LDCT) for lung cancer high-risk population has been proved to improve health outcomes and relieve disease burden efficiently for both individual and society. With geograph...

    Authors: Jay Pan, Jianjian Wang, Wenjuan Tao, Chaohui Wang, Xiaojun Lin, Xiuli Wang and Ruicen Li
    Citation: BMC Cancer 2024 24:342
  4. Adult head and neck rhabdomyosarcoma (HNRMS) is an exceptionally rare malignancy, and there is a paucity of data and research dedicated to understanding its characteristics and management in adult populations....

    Authors: Dan Zhao, Fang Zhou, Weixin Liu, Zhou Huang, Xiaolong Xu, Baomin Zheng, Changqing Liu, Chujie Bai, Jiayong Liu, Yan Sun, Weihu Wang and Shaowen Xiao
    Citation: BMC Cancer 2024 24:340
  5. Beta-(1,3)(1,6)-D-glucan is a complex polysaccharide, which is found in the cell wall of various fungi, yeasts, bacteria, algae, barley, and oats and has immunomodulatory, anticancer and antiviral effects. In the...

    Authors: Abdelhadi Boulifa, Martin J. Raftery, Alexander Sebastian Franzén, Clarissa Radecke, Sebastian Stintzing, Jens-Uwe Blohmer and Gabriele Pecher
    Citation: BMC Cancer 2024 24:339
  6. Patients at risk of skin cancers can develop varying types of cutaneous malignancies. However, some subjects may develop only one type of lesion. In this cross-sectional study, the spectrum of premalignant (PM...

    Authors: Reetta Nevakivi, Hanna Siiskonen, Salla Haimakainen and Ilkka T. Harvima
    Citation: BMC Cancer 2024 24:338
  7. The presence of heterogeneity is a significant attribute within the context of ovarian cancer. This study aimed to assess the predictive accuracy of models utilizing quantitative 18F-FDG PET/CT derived inter-tumo...

    Authors: Dianning He, Xin Zhang, Zhihui Chang, Zhaoyu Liu and Beibei Li
    Citation: BMC Cancer 2024 24:337
  8. After curative surgery for early-stage breast cancer, patients face a decision on whether to undergo surgery alone or to receive one or more adjuvant treatments, which may lower the risk of recurrence. Variati...

    Authors: Bettina Mølri Knudsen, Stine Rauff Søndergaard, Dawn Stacey and Karina Dahl Steffensen
    Citation: BMC Cancer 2024 24:336
  9. The development of drug resistance is a major cause of cancer therapy failures. To inhibit drug resistance, multiple drugs are often treated together as a combinatorial therapy. In particular, synergistic drug...

    Authors: Sijiao Wang, Juliano Oliveira-Silveira, Gang Fang and Jungseog Kang
    Citation: BMC Cancer 2024 24:335
  10. Ribosomal RNA processing protein 15 (RRP15) has been found to regulate the progression of hepatocellular carcinoma (HCC). Nevertheless, the extent to which it contributes to the spread of HCC cells remains unc...

    Authors: Tongtong Pan, Jinhai Li, Ouyang Zhang, Yuqin Zhu, Hongfei Zhou, Mengchen Ma, Yanwen Yu, Jiaojian Lyu, Yongping Chen and Liang Xu
    Citation: BMC Cancer 2024 24:334
  11. Paucity and low evidence-level data on proton therapy (PT) represent one of the main issues for the establishment of solid indications in the PT setting. Aim of the present registry, the POWER registry, is to pro...

    Authors: Daniela Alterio, Maria Giulia Vincini, Stefania Volpe, Luca Bergamaschi, Mattia Zaffaroni, Sara Gandini, Giulia Peruzzotti, Federica Cattani, Cristina Garibaldi, Barbara Alicja Jereczek-Fossa and Roberto Orecchia
    Citation: BMC Cancer 2024 24:333
  12. Almost one third of cancer patients in the United States will develop brain metastases on an annual basis. Surgical resection is indicated in the setting of brain metastases for reasons, such as maximizing loc...

    Authors: David M. Routman, Ignacio Jusue-Torres, Paul D. Brown, Daniel M. Trifiletti, Sujay A. Vora, Desmond A. Brown, Ian F. Parney, Terry C. Burns and Elizabeth Yan
    Citation: BMC Cancer 2024 24:332
  13. Angiogenesis is crucial for tumor development, progression, and metastasizing. The most important regulator of angiogenesis is the vascular endothelial growth factor (VEGF) family, which is involved in multipl...

    Authors: Niina Mäenpää, Leena Tiainen, Mari Hämäläinen, Tiina Luukkaala, Minna Tanner, Outi Lahdenperä, Pia Vihinen, Peeter Karihtala, Pirkko-Liisa Kellokumpu-Lehtinen, Eeva Moilanen and Arja Jukkola
    Citation: BMC Cancer 2024 24:331
  14. TMEFF1 is a new protein involved in the physiological functions of the central nervous system, and we previously reported TMEFF1 can promote ovarian cancer. ST14 was determined to be involved in the processes ...

    Authors: Xin Nie, Lingling Gao, Mingjun Zheng, Shuang Wang, Caixia Wang, Xiao Li, Ouxuan Liu, Rui Gou, Juanjuan Liu and Bei Lin
    Citation: BMC Cancer 2024 24:330
  15. Population-based cancer quality registries are of great importance for the improvement of cancer care. However, little is known about the quality of recurrence data in cancer quality registries. The aim of thi...

    Authors: Sofia Palmér, Carl Blomqvist, Marit Holmqvist, Henrik Lindman, Mats Lambe and Johan Ahlgren
    Citation: BMC Cancer 2024 24:329
  16. The sialic acid binding Ig like lectin 15 (Siglec-15) was previously identified as tumor immune suppressor gene in some human cancers with elusive molecular mechanism to be elucidated. The continuous focus on ...

    Authors: Xingzhi Li, Ziji Liang, Jiexin Pan, Meng Zhang, Jinli Liu, Rong Hu and Caiyan Liao
    Citation: BMC Cancer 2024 24:328
  17. FLI1 is an oncogenic transcription factor that promotes diverse malignancies through mechanisms that are not fully understood. Herein, FLI1 is shown to regulate the expression of Ubiquitin Associated and SH3 D...

    Authors: Jie Wang, Chunlin Wang, Anling Hu, Kunlin Yu, Yi Kuang, Babu Gajendran, Eldad Zacksenhaus, Klarke Michael Sample, Xiao Xiao, Wuling Liu and Yaacov Ben-David
    Citation: BMC Cancer 2024 24:326
  18. T-cell acute lymphoblastic leukemia (T-ALL) is a genetically heterogeneous disease with poor prognosis and inferior outcome. Although multiple studies have been perform on genomics of T-ALL, data from Indian s...

    Authors: Minu Singh, Pankaj Sharma, Prateek Bhatia, Amita Trehan, Rozy Thakur and Sreejesh Sreedharanunni
    Citation: BMC Cancer 2024 24:325
  19. Radiotherapy (RT) is an essential treatment modality against cancer and becoming even more in demand due to the anticipated increase in cancer incidence. Due to the rapid development of RT technologies amid fi...

    Authors: Arefeh Saeedian, Fatemeh-sadat Tabatabaei, Amirali Azimi, Mohammad Babaei, Marzieh Lashkari, Ebrahim Esmati, Zeinab Abiar, Leila Moadabshoar, Saleh Sandoughdaran, Mitchell Kamrava, Arya Amini and Reza Ghalehtaki
    Citation: BMC Cancer 2024 24:324
  20. Increased mitochondrial activities contributing to cancer cell proliferation, invasion, and metastasis have been reported in different cancers; however, studies on the therapeutic targeting of mitochondria in ...

    Authors: Shashank Mathur, Pransu Srivastava, Anubhav Srivastava, Neeraj Kumar Rai, Sabiya Abbas, Ashok kumar, Meenakshi Tiwari and Lokendra Kumar Sharma
    Citation: BMC Cancer 2024 24:323
  21. Liquid biopsy can detect circulating cancer cells or tumor cell-derived DNA at various stages of cancer. The fluid from these biopsies contains extracellular vesicles (EVs), such as apoptotic bodies, microvesi...

    Authors: Mickensone Andre, Allen Caobi, Jana S. Miles, Arti Vashist, Marco A. Ruiz and Andrea D. Raymond
    Citation: BMC Cancer 2024 24:322
  22. Definitive concurrent chemoradiotherapy (dCCRT) is the gold standard for the treatment of locally advanced esophageal squamous cell carcinoma (ESCC). However, the potential benefits of consolidation chemothera...

    Authors: Chengcheng Fan, Xu Wang, Xiaoli Zheng, Yanan Sun, Ke Ye, Yue Jiang, Xiao Liu, Wencai Xu, Yang Liu, Yuanyuan Yang, Jinsong Liu, Qiong Jiang, Chunyu He, Xiaoyuan Wu, Xin Nie, Jingwei Zhang…
    Citation: BMC Cancer 2024 24:321
  23. Chronic kidney disease (CKD) is highly connected to inflammation and oxidative stress. Both favour the development of cancer in CKD patients. Serum apolipoprotein A-IV (apoA-IV) concentrations are influenced b...

    Authors: Barbara Kollerits, Simon Gruber, Inga Steinbrenner, Johannes P. Schwaiger, Hansi Weissensteiner, Sebastian Schönherr, Lukas Forer, Fruzsina Kotsis, Ulla T. Schultheiss, Heike Meiselbach, Christoph Wanner, Kai-Uwe Eckardt and Florian Kronenberg
    Citation: BMC Cancer 2024 24:320
  24. The histological grade is an important factor in the prognosis of invasive breast cancer and is vital to accurately identify the histological grade and reclassify of Grade2 status in breast cancer patients.

    Authors: Deyong Kang, Chuan Wang, Zhonghua Han, Liqin Zheng, Wenhui Guo, Fangmeng Fu, Lida Qiu, Xiahui Han, Jiajia He, Lianhuang Li and Jianxin Chen
    Citation: BMC Cancer 2024 24:318
  25. Glioblastoma multiforme (GBM) is the most aggressive form of brain cancer, and chemoresistance poses a significant challenge to the survival and prognosis of GBM. Although numerous regulatory mechanisms that c...

    Authors: Jiao Meng, Wei Qian, Zhenkun Yang, Lingli Gong, Daxing Xu, Hongbo Huang, Xinyi Jiang, Zhening Pu, Ying Yin and Jian Zou
    Citation: BMC Cancer 2024 24:317
  26. Breast cancer (BC) is the most common cancer affecting women globally. Genetic testing serves as a prevention and treatment strategy for managing BC. This study aims to systematically review economic evaluatio...

    Authors: Sook Pin Goh, Siew Chin Ong and Jue Ern Chan
    Citation: BMC Cancer 2024 24:316
  27. Rectal tumor segmentation on post neoadjuvant chemoradiotherapy (nCRT) magnetic resonance imaging (MRI) has great significance for tumor measurement, radiomics analysis, treatment planning, and operative strat...

    Authors: Shaojun Xia, Qingyang Li, Hai-Tao Zhu, Xiao-Yan Zhang, Yan-Jie Shi, Ding Yang, Jiaqi Wu, Zhen Guan, Qiaoyuan Lu, Xiao-Ting Li and Ying-Shi Sun
    Citation: BMC Cancer 2024 24:315
  28. Transversal approach for robotic-assisted radical prostatectomy via a bladder neck and prostate combined longitudinal incision (L-RALP) is a novel surgical method for patients with respectable prostate cancer.

    Authors: Zefan Shen, CenChao Yao, YuChen Bai, YiFan Wang and Qi Zhang
    Citation: BMC Cancer 2024 24:313
  29. There are differences in the pharmacoeconomics of Immune checkpoint blocking (ICB) therapies for the treatment of lung squamous cell carcinoma (LSCC). However, no corresponding review studies have fully discus...

    Authors: Minyu Cheng, Yanfei Shao, Li Li, Menglao Jiang and Zhouye Song
    Citation: BMC Cancer 2024 24:312
  30. For drugs reimbursed with limited evidence of patient benefits, confirmatory evidence of overall survival (OS) and quality of life (QoL) benefits is important. For QoL data to serve as valuable input to patien...

    Authors: Mikael Svensson, Gabriella Chauca Strand, Carl Bonander, Naimi Johansson and Niklas Jakobsson
    Citation: BMC Cancer 2024 24:311
  31. Invasive breast cancer (IBC) is a leading cause of cancer-related death among women in Israel, regardless of ethnicity. This study compared IBC epidemiological, clinical, and pathological characteristics in Be...

    Authors: Itamar Ben Shitrit, Ao Wang, Karny Ilan, Ravit Agassi, Sofyan Abu Freih and Julie Vaynshtein
    Citation: BMC Cancer 2024 24:310
  32. Cancer incidence and mortality vary across the globe, with nearly two-thirds of cancer-related deaths occurring in low- and middle-income countries. The rural-urban disparity in socio-demographic, behavioural,...

    Authors: Divya Khanna, Priyanka Sharma, Atul Budukh, Rajesh Vishwakarma, Anand N. Sharma, Sonali Bagal, Varsha Tripathi, Vijay Kumar Maurya, Pankaj Chaturvedi and Satyajit Pradhan
    Citation: BMC Cancer 2024 24:308
  33. Preoperative prediction of International Federation of Gynecology and Obstetrics (FIGO) stage in patients with epithelial ovarian cancer (EOC) is crucial for determining appropriate treatment strategy. This st...

    Authors: Yinping Leng, Ao Kan, Xiwen Wang, Xiaofen Li, Xuan Xiao, Yu Wang, Lan Liu and Lianggeng Gong
    Citation: BMC Cancer 2024 24:307
  34. Patients with hepatocellular carcinoma (HCC) who undergo transarterial chemoembolization (TACE) may have varied outcomes based on their liver function and tumor burden diversity. This study aims to assess the ...

    Authors: Jiawei Lin, Jie Li, Yifan Kong, Junhui Yang, Yunjie Zhang, Guoqing Zhu, Zhijie Yu and Jinglin Xia
    Citation: BMC Cancer 2024 24:306
  35. A consensus has not been reached on the value of prostate-specific antigen density (PSAD) as a predictor of biochemical recurrence of prostate cancer. This meta-analysis aimed to evaluate the association betwe...

    Authors: Feilun Cui, Yue Qiu, Wei Xu, Chen Zou and Yu Fan
    Citation: BMC Cancer 2024 24:305
  36. To analyze the efficacy of stereotactic ablative brachytherapy (SABT) and percutaneous microwave ablation (MWA) for the treatment of early-stage non-small cell lung cancer (NSCLC).

    Authors: Chuanwang Wu, Binglong Cao, Guanghui He, Yuliang Li and Wujie Wang
    Citation: BMC Cancer 2024 24:304
  37. Soft tissue sarcomas (STSs) are a heterogeneous group of tumors. Wide surgical resection is standard, often combined with neoadjuvant chemotherapy, radiotherapy, or both. Studies have shown the predictive valu...

    Authors: Julian Fromm, Alexander Klein, Maya Kirilova, Lars Hartwin Lindner, Silke Nachbichler, Boris Michael Holzapfel, Sophia Samira Goller, Thomas Knösel and Hans Roland Dürr
    Citation: BMC Cancer 2024 24:303
  38. There are various recommendations for third-line treatment in mCRC, however, there is no consensus on who is more suitable for particular strategy. Chemotherapy re-use in third-line setting is a common option ...

    Authors: Jingjing Duan, Lila Zhu, Yinghui Shi, Weixue Wang, Tongtong Wang, Tao Ning, Le Zhang, Ming Bai, Hongli Li, Rui Liu, Shaohua Ge, Xia Wang, Yuchong Yang, Zhi Ji, Feixue Wang, Yansha Sun…
    Citation: BMC Cancer 2024 24:302
  39. Consensus/evidence-based recommendations for assessing, managing, and monitoring bone health, pain, and mobility in patients with multiple myeloma were developed. This study was conducted to assess the adheren...

    Authors: Ramzi Shawahna, Riad Amer, Husam Salameh, Abdul-Rahman Shawahna, Mohmmad Aljondy and Mohmmad Zain-Aldain
    Citation: BMC Cancer 2024 24:301
  40. The quality of life of patients is an important consideration when selecting treatments for localized prostate cancer (PCa). We retrospectively compared sexual function after robot-assisted radical prostatecto...

    Authors: Yoshiyuki Miyazawa, Hidekazu Koike, Daisuke Oka, Hidemasa Kawamura, Nobuteru Kubo, Yuhei Miyasaka, Masahiro Onishi, Takahiro Syuto, Yoshitaka Sekine, Hiroshi Matsui, Tatsuya Ohno and Kazuhiro Suzuki
    Citation: BMC Cancer 2024 24:300
  41. CT examination for lung cancer has been carried out for more than 20 years and great achievements have been made in the early detection of lung cancer. However, in the clinical work, a large number of advanced...

    Authors: Jiaming Zhou, Bijun Yu, Peng Guo and Shi Wang
    Citation: BMC Cancer 2024 24:299
  42. The surge in the utilization of CT scans for COVID-19 diagnosis and monitoring during the pandemic is undeniable. This increase has brought to the forefront concerns about the potential long-term health conseq...

    Authors: Golshan Mahmoudi, Heidar Toolee, Reza Maskani, Farzaneh Jokar, Milad Mokfi and Ali Hosseinzadeh
    Citation: BMC Cancer 2024 24:298
  43. IgG4, which plays a pivotal role in the progression of phenotypically diverse tumors, serves as a prognostic marker because of its influence on cancer immunity. Nevertheless, the functions of IgG4 in tongue sq...

    Authors: Hironobu Fukuda, Takeshi Uehara, Tomoyuki Nakajima, Mai Iwaya, Shiho Asaka and Hiroshi Kurita
    Citation: BMC Cancer 2024 24:294

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