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  1. Trastuzumab is the only approved target agent for the first-line treatment of human epidermal growth factor receptor-2 (HER-2) positive gastric cancer; however, trastuzumab resistance is a major problem in cli...

    Authors: Yuna Kim, Yoo Jin Bae, Jie-Hyun Kim, Hyunki Kim, Su-Jin Shin, Da Hyun Jung and Hyojin Park
    Citation: BMC Cancer 2023 23:922
  2. Phospholipase C Delta 3 (PLCD3) is a member of phospholipase C(PLC) Protein and PLCD3 protein plays a prominent role in many cancers. However, little is known about the role of PLCD3 in esophageal squamous cel...

    Authors: Mengmeng Wang, Mingjun Gao, Yong Chen, Jun Wu, Xiaolin Wang and Yusheng Shu
    Citation: BMC Cancer 2023 23:921
  3. Despite major advances in cancer therapeutics, the therapeutic options of Lung Squamous Cell Carcinoma (LSCC)-specific remain limited. Furthermore, the current staging system is imperfect for defining a progno...

    Authors: Chen-ye Shao, Jing Luo, Sheng Ju, Chu-ling Li, Cheng Ding, Jun Chen, Xiao-long Liu, Jun Zhao and Li-qin Yang
    Citation: BMC Cancer 2023 23:920
  4. This retrospective analysis of data from clinical trials in metastatic urothelial carcinoma (mUC) was conducted to determine baseline patient characteristics associated with long-term survival (LTS) following ...

    Authors: Marie Alt, Carlos Stecca, Yian Lin, Gbenga Kazeem, Erik T. Goluboff and Srikala S. Sridhar
    Citation: BMC Cancer 2023 23:919
  5. Understanding how patient-reported experiences of care and overall rating of care vary among patients with different characteristics is useful to help interpret results from patient experience surveys and desi...

    Authors: Chantal Arditi, Manuela Eicher, Julien Junod and Isabelle Peytremann-Bridevaux
    Citation: BMC Cancer 2023 23:918
  6. Although research has advanced the field of oncologic geriatrics with survivors to assess their cancer-related needs and devise patient-centered interventions, most of that research has excluded rural populati...

    Authors: Evelyn Arana-Chicas, Laura M. Hincapie Prisco, Saloni Sharma, Fiona Stauffer, Martha McGee, Serge Dauphin, Makiko Ban-Hoefen, Jaime Navarette, Jason Zittel, Ana Paula Cupertino, Allison Magnuson, Karen M. Mustian and Supriya G. Mohile
    Citation: BMC Cancer 2023 23:917
  7. Concomitant diseases often occur in cancer patients and are important in decision-making regarding treatments. However, information regarding the prognostic relevance of comorbidities for mortality risk is sti...

    Authors: Ju Wu, Simiao Tian, Jian Xu, Nan Cheng, Xi Chen, Jiajun Yin and Zhequn Nie
    Citation: BMC Cancer 2023 23:916
  8. Whether serum lactate dehydrogenase-to-albumin ratio (LAR) influenced the outcomes of colorectal cancer (CRC) patients after radical surgery remained unclear. Therefore, this study sought to examine how LAR in...

    Authors: Xin-Peng Shu, Ying-Chun Xiang, Fei Liu, Yong Cheng, Wei Zhang and Dong Peng
    Citation: BMC Cancer 2023 23:915
  9. The negative effects of the novel coronavirus disease 2019 (COVID-19) pandemic on patients with gastric cancer are poorly understood. This study was designed to compare the short-term and long-term outcomes of...

    Authors: Yong Sun, Chao Chen, Lei Hou and Enhong Zhao
    Citation: BMC Cancer 2023 23:913
  10. Long non-coding RNAs (lncRNAs) play important roles in many pathophysiological processes, including cancer progression. Namely, lncRNA Receptor-tyrosine-kinase-like orphan receptor-1 antisense 1 (ROR1-AS1) is ...

    Authors: Xueliang Li, Zhaowei Sun, Li Wang, Qinlei Wang, Maobing Wang, Jingyun Guo, Haoran Li, MenShou Chen, Guanghua Cao, Yanan Yu, Haochen Zhong, Hao Zou, Kai Ma, Bingyuan Zhang, Guolei Wang and Yujie Feng
    Citation: BMC Cancer 2023 23:912
  11. The goal of therapy for many patients with advanced stage malignancies, including those with metastatic gastric and esophageal cancers, is to extend overall survival while also maintaining quality of life. Aft...

    Authors: Xiaoyuan Ma, Eric Pierce, Harsh Anand, Natalie Aviles, Paul Kunk and Negin Alemazkoor
    Citation: BMC Cancer 2023 23:910
  12. Well-differentiated (WD) neuroendocrine tumors (NETs) are a group of rare neoplasms with limited therapeutic options. Cabozantinib is an inhibitor of multiple tyrosine kinases with a pivotal role in NET pathog...

    Authors: Francesca Corti, Maria Pia Brizzi, Vito Amoroso, Dario Giuffrida, Francesco Panzuto, Davide Campana, Natalie Prinzi, Massimo Milione, Tommaso Cascella, Carlo Spreafico, Giovanni Randon, Simone Oldani, Rita Leporati, Giulia Scotto, Iolanda Pulice, Benedetta Lombardi Stocchetti…
    Citation: BMC Cancer 2023 23:908
  13. Heterozygous isocitrate dehydrogenase (IDH) mutations occur in about half of conventional central bone chondrosarcomas (CCBC). Aim of this study was to assess the frequency and prognostic impact of IDH mutations ...

    Authors: Elisabetta Setola, S. Benini, A. Righi, G. Gamberi, E. Carretta, C. Ferrari, S. Avnet, E. Palmerini, G. Magagnoli, M. Gambarotti, P. L. Lollini, M. Cesari, S. Cocchi, A. Paioli, A. Longhi, K. Scotlandi…
    Citation: BMC Cancer 2023 23:907
  14. Hepatocellular carcinoma (HCC), the most common primary liver cancer, prevails mainly in males and has long been attributed to androgens and higher circumstantial levels of interleukin-6 (IL-6) produced by res...

    Authors: Yahong Xu, Yongjie Zhu, Zhenru Wu, Shengfu Li, Mingyang Shao, Qing Tao, Qing Xu, Yuwei Chen, Yuke Shu, Menglin Chen, Yongjie Zhou and Yujun Shi
    Citation: BMC Cancer 2023 23:906
  15. We aimed to evaluate the clinical efficacy and prognostic significance of intensity-modulated radiotherapy (IMRT)-based salvage concurrent chemoradiotherapy (CCRT) for patients with locoregional recurrence cer...

    Authors: Minjie Shan, Yuping Deng, Wen Zou, Shasha Fan, Yanlong Li, Xianling Liu and Jingjing Wang
    Citation: BMC Cancer 2023 23:905
  16. Cancer survival rates are increasing; however, studies on dyslipidemia as a comorbidity of cancer are limited. For efficient management of the disease burden, this study aimed to understand new-onset dyslipide...

    Authors: Yun Hwa Jung, IL Yun, Eun-Cheol Park and Sung-In Jang
    Citation: BMC Cancer 2023 23:904
  17. Cytoreductive surgery (CRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC) is the standard treatment for pseudomyxoma peritonei (PMP). It can significantly prolong the survival of patients, but at the ...

    Authors: Rui Yang, Xin Zhao, Yu-Bin Fu, Yu-Lin Lin, Ru Ma, Yan-Dong Su, He-Liang Wu, Xin-Li Liang and Yan Li
    Citation: BMC Cancer 2023 23:903
  18. The ALTA-1L study compared brigatinib with crizotinib in untreated ALK-rearranged non-small cell lung cancer (NSCLC) patients, demonstrating the efficacy of brigatinib. Although the median progression-free surviv...

    Authors: Kazushige Wakuda, Hirotsugu Kenmotsu, Yuki Sato, Atsushi Nakamura, Hiroaki Akamatsu, Motoko Tachihara, Satoru Miura, Toshihide Yokoyama, Keita Mori, Kazuhiko Nakagawa and Nobuyuki Yamamoto
    Citation: BMC Cancer 2023 23:902
  19. The application of coagulation-related markers in laryngeal squamous cell carcinoma(LSCC) remains unclear. This study explored the prognostic role of coagulation markers in the progression and metastasis of LSCC.

    Authors: Qiongling Huang, Jing Chen, Yanjun Huang, Yu Xiong, Jiao Zhou, Yizheng Zhang, Ming Lu, Weipeng Hu, Feng Zheng and Chaohui Zheng
    Citation: BMC Cancer 2023 23:901
  20. Early-stage colorectal cancer had excellent outcomes after curative resection, typically. However, a perplexing survival paradox between stage II and stage III was noted. This paradox could be influenced by th...

    Authors: Yen-Lin Yu, Wen-Ko Tseng, Chun-Kai Liao, Chien-Yuh Yeh, Hong-Hwa Chen, Yu-Hsuan Liu, Yu-Wei Liaw and Chung-Wei Fan
    Citation: BMC Cancer 2023 23:900
  21. Studies have demonstrated that Sorting nexin 7 (SNX7) functions as an anti-apoptotic protein in liver tissue and plays a crucial role in the survival of hepatocytes during early embryonic development. However,...

    Authors: Jianlin Chen, Gan Gao, Yi Zhang, Peng Dai and Yi Huang
    Citation: BMC Cancer 2023 23:899
  22. Long non-coding RNAs play an important role in the development of colorectal cancer (CRC), while many CRC-related lncRNAs have not yet been identified.

    Authors: Ganglin Ren, Hongyan Li, Dan Hong, Fangyu Hu, Rongjia Jin, Shuang Wu, Wenhao Sun, Honglei Jin, Lingling Zhao, Xiaodong Zhang, Dongxiang Liu, Chuanshu Huang and Haishan Huang
    Citation: BMC Cancer 2023 23:898
  23. Lung adenocarcinoma (LUAD) is an extraordinarily malignant tumor, with rapidly increasing morbidity and poor prognosis. Immunotherapy has emerged as a hopeful therapeutic modality for lung adenocarcinoma. Furt...

    Authors: Qianhe Ren, Qifan Li, Chenye Shao, Pengpeng Zhang, Zhuangzhuang Hu, Jun Li, Wei Wang and Yue Yu
    Citation: BMC Cancer 2023 23:897
  24. The dense stroma of pancreatic ductal adenocarcinomas is a major barrier to drug delivery. To increase the local drug diffusion gradient, high doses of chemotherapeutic agent doxorubicin can be released from t...

    Authors: Laura Spiers, Michael Gray, Paul Lyon, Shivan Sivakumar, Noor Bekkali, Shaun Scott, Linda Collins, Robert Carlisle, Feng Wu, Mark Middleton and Constantin Coussios
    Citation: BMC Cancer 2023 23:896
  25. Although a long-term goal of cancer therapy always has been the development of agents that selectively destroy cancer cells, more recent trends have been to seek secondary agents that sensitize cancer cells to...

    Authors: D. Alimbetov, B. Umbayev, A. Tsoy, D. Begimbetova, T. Davis, D. Kipling and Sh. Askarova
    Citation: BMC Cancer 2023 23:895
  26. The incidence of peripherally inserted central catheter (PICC)-related complications is higher in cancer patients than in noncancer patients. However, the pattern of specific complication occurrence over time ...

    Authors: Ruixia Liu, Huiqiong Xu, Lihui Pu, Xiaofeng Xie, Hongxiu Chen, Zhoupeng Wu, Huirong Chen and Xiaoxia Zhang
    Citation: BMC Cancer 2023 23:894
  27. Pancreatic cancer is a growing public health concern in China, and depicting it from different perspectives would provide a comprehensive understanding of its epidemiological characteristics.

    Authors: Yangyang Xu, Wei Liu, Zheng Long, Lijun Wang, Maigeng Zhou and Peng Yin
    Citation: BMC Cancer 2023 23:893
  28. The current National Comprehensive Cancer Network (NCCN) guidelines recommend that at least 16 lymph nodes should be examined for gastric cancer patients to reduce staging migration. However, there is still de...

    Authors: Lulu Zhao, Fan Zhang, Fuzhi Jiao, Xiadong Zhou, Penghui Niu, Xue Han, Wanqing Wang, Xiaoyi Luan, Mingyan He, Quanlin Guan, Yumin Li, Dongbing Zhao, Jidong Gao and Yingtai Chen
    Citation: BMC Cancer 2023 23:892
  29. For patients with pancreatic ductal adenocarcinoma (PDAC), surgical resection remains the only potentially curative treatment. Surgery is generally followed by postoperative chemotherapy associated with improv...

    Authors: Christelle Bouchart, Julie Navez, Ivan Borbath, Karen Geboes, Timon Vandamme, Jean Closset, Luigi Moretti, Pieter Demetter, Marianne Paesmans and Jean-Luc Van Laethem
    Citation: BMC Cancer 2023 23:891
  30. The expansion of antiretroviral therapy (ART) eligibility could lead to earlier initiation of Human Immunodeficiency Virus (HIV) treatment and consequently reduce the risk of HIV-associated Kaposi Sarcoma (KS)...

    Authors: Maxwell. O. Akanbi, Lucy. A. Bilaver, Chad Achenbach, Lisa. R. Hirschhorn, Adovich. S. Rivera, Orimisan. S. Adekolujo, Kehinde. U. A. Adekola, Olugbenga. A. Silas, Patricia. A. Agaba, Oche Agbaji, Nathan. Y. Shehu, Solomon. A. Sagay, Lifang Hou and Robert. L. Murphy
    Citation: BMC Cancer 2023 23:890
  31. Exerkines are all peptides, metabolites, and nucleic acids released into the bloodstream during and after physical exercise. Exerkines liberated from skeletal muscle (myokines), the heart (cardiokines), liver ...

    Authors: Amirhossein Ahmadi Hekmatikar, André Nelson and Aaron Petersen
    Citation: BMC Cancer 2023 23:889
  32. Endometrial carcinoma (EC) is one of the most commonly diagnosed gynecologic malignancy in China. However, the genetic profile of Chinese EC patients has not been well established yet.

    Authors: Jin Li, Xiaoqi Li, Chenlian Quan, Xiaoqiu Li, Chong Wan and Xiaohua Wu
    Citation: BMC Cancer 2023 23:888
  33. The relationship between migraine and breast cancer risk has generated conflicting findings. We attempted to assess the association between migraine and breast cancer risk using Mendelian randomization (MR) an...

    Authors: Tian Fang, Zhihao Zhang, Huijie Zhou, Wanchun Wu, Fuqing Ji and Liqun Zou
    Citation: BMC Cancer 2023 23:887
  34. Glioblastoma (GBM), a prevalent and malignant brain tumor, poses a challenge in surgical resection due to its invasive nature within the brain parenchyma. CDKN1A (p21, Waf-1), a cyclin-dependent kinase inhibit...

    Authors: Wen-Yu Cheng, Chiung-Chyi Shen, Yea-Jiuen Liang, Ming-Tsang Chiao, Yi-Chin Yang, Wan-Yu Hsieh, Cheng-Hui Lin and Jun-Peng Chen
    Citation: BMC Cancer 2023 23:886
  35. Bladder and urinary tract cancers account for approximately 21,000 new diagnoses and 5,000 deaths annually in the UK. Approximately 90% are transitional cell carcinomas where advanced disease is treated with p...

    Authors: Simon Crabb, Robin Wickens, Sarah Jane-Bibby, Denise Dunkley, Megan Lawrence, Allen Knight, Robert Jones, Alison Birtle, Robert Huddart, Mark Linch, Jonathan Martin, Adam Coleman, Konstantinos Boukas, Hannah Markham and Gareth Griffiths
    Citation: BMC Cancer 2023 23:885
  36. The relationship between sleep disturbances and lung cancer is complex and bidirectional. This meta-epidemiological study aimed to explore the potential association between sleep disruption and the risk of pul...

    Authors: Tong Zhou, Zichen Wang, Chenxi Qiao, Shuo Wang, Shuaihang Hu, Xinyan Wang, Xiumei Ma, Dandan Wang, Jinglei Li, Zheng Li and Wei Hou
    Citation: BMC Cancer 2023 23:884
  37. Triple negative breast cancers (TNBC) account for approximately 15% of all breast cancers and are associated with a shorter median survival mainly due to locally advanced tumor and high risk of metastasis. The...

    Authors: Jordane Divoux, Romane Florent, Margaux Jacobs, Justine Lequesne, Jean-Michel Grellard, Chankannira San, Sara Grossi, Katia Kerdja, Bénédicte Clarisse, Gwenaelle Boudier, François Cherifi, Mélanie Briand, Enora Dolivet, Alisson Johnson, Brice Dubois, Valentin Harter…
    Citation: BMC Cancer 2023 23:883
  38. Thyroid cancer (TC) is one of the most common endocrine malignancies, and its morbidity continues to rise. N6-methyladenosine (m6A) RNA methylation, an epigenetic modification, is an important regulator of gene e...

    Authors: Yihan Zhang, Ying Chen, Ruihua Chen, Hong Zhou, Yi Lin, Bingxin Li, Huaidong Song, Guoqiang Zhou, Mei Dong and Huanbai Xu
    Citation: BMC Cancer 2023 23:882
  39. Breast cancer is the commonest cancer among women in India, yet the uptake of early detection programs is poor. This leads to late presentation, advanced stage at the time of diagnosis, and high mortality. Poo...

    Authors: Riya Sawhney, Priyansh Nathani, Priti Patil, Prashant Bhandarkar, Deepa Kizhakke Veetil, Jubina Balan Venghateri, Nobhojit Roy and Anita Gadgil
    Citation: BMC Cancer 2023 23:881
  40. Guidelines recommend total thyroidectomy (TT) to facilitate radioactive ablation and serological follow-up for intermediate- to high-risk papillary thyroid carcinoma (PTC). However, the association between sur...

    Authors: Siyuan Xu, Hui Huang, Huilei Dong, Xiaolei Wang, Zhengang Xu, Shaoyan Liu and Jie Liu
    Citation: BMC Cancer 2023 23:880
  41. The epithelial-mesenchymal transition (EMT) plays an indispensable role in the development and progression of Endometrial cancer (EC). Nevertheless, little evidence is reported to uncover the functionality and...

    Authors: Yonghui Yu, Yiwen Zhang, Zhi Li, Yongshun Dong, Hongmei Huang, Binyao Yang, Eryong Zhao, Yongxiu Chen, Lei Yang, Jiachun Lu and Fuman Qiu
    Citation: BMC Cancer 2023 23:879
  42. Colorectal cancer (CRC) is one of the malignant tumors with the highest morbidity and mortality and poor prognosis. The mammalian gene family of Cab45/reticulocalbin/ERC-45/calumenin (CREC) consists of RCN1, R...

    Authors: Junya Ning, Min Liu, Jing Shen, Deping Wang, Lijuan Gao, Huiyu Li and Jimin Cao
    Citation: BMC Cancer 2023 23:878
  43. Real-world data on treatment patterns/outcomes for metastatic pancreatic cancer (mPAC) are limited. This study aims to assess real-world treatment patterns, survival outcomes, and prognostic/predictive factors...

    Authors: Julien Taieb, Thomas Seufferlein, Michele Reni, Daniel H. Palmer, John A. Bridgewater, Antonio Cubillo, Gerald W. Prager, Alice Vermeire, Fabienne Hédouin-Biville, Zhaoyang Teng and Teresa Macarulla
    Citation: BMC Cancer 2023 23:877
  44. Pancreatic cancer poses a serious medical problem worldwide. Countries in the Western Pacific Region are facing public health challenges from cancer. This study assesses the time trends of pancreatic cancer mo...

    Authors: Wenkai Jiang, Caifei Xiang, Yan Du, Xiao Li, Xin Li and Wence Zhou
    Citation: BMC Cancer 2023 23:876
  45. Telomeres are repetitive DNA sequences located at the ends of chromosomes, playing a vital role in maintaining chromosomal integrity and stability. Dysregulation of telomeres has been implicated in the develop...

    Authors: Gh. Rasool Bhat, Rajeshwer Singh Jamwal, Itty Sethi, Amrita Bhat, Ruchi Shah, Sonali Verma, Minerva Sharma, Hana Q. Sadida, Sara K. Al-Marzooqi, Tariq Masoodi, Sameer Mirza, Mohammad Haris, Muzafar A. Macha, Ammira S. Alshabeeb Akil, Ajaz A. Bhat and Rakesh Kumar
    Citation: BMC Cancer 2023 23:874
  46. The aim of the present study was to assess the efficacy and safety of transarterial chemoembolization (TACE) combined with atezolizumab and bevacizumab (hereafter, TACE-Atez/Bev) in the treatment of advanced h...

    Authors: Fei Cao, Changsheng Shi, Guofu Zhang, Jun Luo, Jiaping Zheng and Weiyuan Hao
    Citation: BMC Cancer 2023 23:873
  47. Lung cancer is a major global threat to public health for which a novel predictive nomogram is urgently needed. Non-small cell lung cancer (NSCLC) which accounts for the main port of lung cancer cases is attra...

    Authors: Zufang Liao, Rongjiong Zheng, Ni Li and Guofeng Shao
    Citation: BMC Cancer 2023 23:872

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