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  1. Kidney transplantation (KT) correlates with an increased risk of developing several malignancies; however, the risk of colorectal cancer (CRC) after KT remains debatable and has been marginally explored. Hence...

    Authors: Han-En Wang, Yu-Chan Liao, Je-Ming Hu, Wen-Chih Wu, Wan-Yun Chou, Yong-Chen Chen, Yu-Ching Chou, Chi-Feng Hung, Yu-Feng Tian, San-Lin You and Chien-An Sun

    Citation: BMC Cancer 2019 19:1120

    Content type: Research article

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  2. Intracranial metastasis of Gastrointestinal Stromal Tumors (GISTs) is rare but presents unique treatment challenges. We present a case of intracranial metastasis of GIST with a systematic review of the literat...

    Authors: Marc Prablek, Visish M. Srinivasan, Aditya Srivatsan, Stephanie Holdener, Mazen Oneissi, Kent A. Heck, Ali Jalali, Jacob Mandel, Ashwin Viswanathan and Akash J. Patel

    Citation: BMC Cancer 2019 19:1119

    Content type: Case report

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  3. Chemotherapy-induced nausea and vomiting (CINV) belong among the most burdensome side effects in hemato-oncology. Mostly, a combination of ondansetron and dexamethasone is used as antiemetic prophylaxis in ped...

    Authors: Semjon Willier, Karin Melanie Cabanillas Stanchi, Martina von Have, Vera Binder, Franziska Blaeschke, Judith Feucht, Tobias Feuchtinger and Michaela Döring

    Citation: BMC Cancer 2019 19:1118

    Content type: Research article

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  4. The CAO/ARO/AIO-94 demonstrated that neoadjuvant chemoradiotherapy (CRT) could decrease the rate of local recurrence rather than distal metastases in advanced rectal cancer. Adjuvant chemotherapy (ACT) can eli...

    Authors: Qingguo Li, Dakui Luo, Ji Zhu, Lifeng Yang, Qi Liu, Yanlei Ma, Lei Liang, Sanjun Cai, Zhen Zhang and Xinxiang Li

    Citation: BMC Cancer 2019 19:1117

    Content type: Study protocol

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  5. Glioma is a common malignant tumours in the central nervous system (CNS), that exhibits high morbidity, a low cure rate, and a high recurrence rate. Currently, immune cells are increasingly known to play roles...

    Authors: Qiu-Yue Zhong, Er-Xi Fan, Guang-Yong Feng, Qi-Ying Chen, Xiao-Xia Gou, Guo-Jun Yue and Gui-hai Zhang

    Citation: BMC Cancer 2019 19:1116

    Content type: Database

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  6. The aim was to investigate the prognostic value of MR apparent diffusion coefficients (ADC) using histogram analysis (HA) in predicting disease-free survival (DFS) of cervical cancer after chemo-radiation ther...

    Authors: Bo Zhao, Kun Cao, Xiao-Ting Li, Hai-Tao Zhu and Ying-Shi Sun

    Citation: BMC Cancer 2019 19:1115

    Content type: Research article

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  7. We investigated the association of LHR expression in epithelial ovarian cancer (OC) with clinical and pathologic characteristics of patients. LHR expression was examined immunohistochemically using tissue micr...

    Authors: Shigang Xiong, Paulette Mhawech-Fauceglia, Denice Tsao-Wei, Lynda Roman, Rajesh K. Gaur, Alan L. Epstein and Jacek Pinski

    Citation: BMC Cancer 2019 19:1114

    Content type: Research article

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  8. Following publication of the original article [1], the authors have re-evaluated the authorship for this article. The updated author group is:

    Authors: Ho-Keun Kwon, Ji-Sun Hwang, Jae-Seon So, Choong-Gu Lee, Anupama Sahoo, Jae-Ha Ryu, Won Kyung Jeon, Byoung Seob Ko, Sung Haeng Lee, Zee Yong Park and Sin-Hyeog Im

    Citation: BMC Cancer 2019 19:1113

    Content type: Correction

    Published on:

    The original article was published in BMC Cancer 2010 10:392

  9. Osteosarcoma (OS) is a malignancy of the bone that has no clearly identified prognostic factors for diagnosis. In this study, we evaluated the regulatory role of long non-coding RNA (lncRNA) ANCR on the migrat...

    Authors: Bo Liu, Hongyan Zhao, Lili Zhang and Xuefeng Shi

    Citation: BMC Cancer 2019 19:1112

    Content type: Research article

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  10. The majority of patients with head and neck squamous cell carcinoma (HNSCC) receive bilateral elective nodal irradiation (ENI), in order to reduce the risk of regional failure. Bilateral ENI, as compared to un...

    Authors: Pieter D. de Veij Mestdagh, Willem H. Schreuder, Wouter V. Vogel, Maarten L. Donswijk, Eric van Werkhoven, Jacqueline E. van der Wal, Richard Dirven, Baris Karakullukcu, Jan-Jakob Sonke, Michiel W. M. van den Brekel, Corrie A. M. Marijnen and Abrahim Al-Mamgani

    Citation: BMC Cancer 2019 19:1110

    Content type: Study protocol

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  11. Circulating tumour DNA (ctDNA) has emerged as a promising blood-based biomarker for monitoring disease status of patients with advanced cancers. The presence of ctDNA in the blood is a result of biological pro...

    Authors: Leslie Calapre, Lydia Warburton, Michael Millward and Elin S. Gray

    Citation: BMC Cancer 2019 19:1109

    Content type: Case report

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  12. To explore the patterns of failures and areas at highest risk of recurrence for postoperative intrahepatic cholangiocarcinoma (IHCC), with the aim to guide IHCC adjuvant radiotherapy.

    Authors: Wei Yu, Chunxiu Hu, Yongjie Shui, Kui Wu, Lili Zhang, Ying Chen, Chao Li, Jing Xu and Qichun Wei

    Citation: BMC Cancer 2019 19:1108

    Content type: Research article

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  13. Multiple endocrine neoplasia type 1 (MEN1) is a rare autosomal dominant inherited condition affecting multiple endocrine organs, resulting in significant morbidity and decreased life expectancy. Early tumor id...

    Authors: Lei Lou, Lixia Zhou, Wenyan Wang, Huina Li and Yuehong Li

    Citation: BMC Cancer 2019 19:1107

    Content type: Case report

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  14. Chemoresistance is an obstacle to the successful treatment of nasopharyngeal carcinoma (NPC). Lapatinib is a targeted tyrosine kinase inhibitor therapeutic drug also used to treat NPC, but high doses are often...

    Authors: Sathid Aimjongjun, Zimam Mahmud, Yannasittha Jiramongkol, Glowi Alasiri, Shang Yao, Ernesto Yagüe, Tavan Janvilisri and Eric W.-F. Lam

    Citation: BMC Cancer 2019 19:1106

    Content type: Research article

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  15. The prevalence of both atrial fibrillation (AF) and malignancies are increasing in the elderly, but incidences of new onset AF in different cancer subtypes are not well described.The objectives of this study w...

    Authors: Christina Boegh Jakobsen, Morten Lamberts, Nicholas Carlson, Morten Lock-Hansen, Christian Torp-Pedersen, Gunnar H. Gislason and Morten Schou

    Citation: BMC Cancer 2019 19:1105

    Content type: Research article

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  16. The relationship between whole brain radiotherapy (WBRT) dose with intracranial tumor control and overall survival (OS) in patients with non-small cell lung cancer (NSCLC) brain metastases (BM) is largely unkn...

    Authors: Zhensheng Li, Dongxing Shen, Jian Zhang, Jun Zhang, Fang Yang, Deyou Kong, Jie Kong and Andu Zhang

    Citation: BMC Cancer 2019 19:1104

    Content type: Research article

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  17. Recently, a growing number of studies have reported the coorelation between miR-155 and the diagnosis and prognosis of lung cancer, but results of these researches were still controversial due to insufficient ...

    Authors: Chuchu Shao, Fengming Yang, Zhiqiang Qin, Xinming Jing, Yongqian Shu and Hua Shen

    Citation: BMC Cancer 2019 19:1103

    Content type: Research article

    Published on:

  18. The combination of nivolumab, a programmed death-1 (PD-1) targeted monoclonal antibody, with the cytotoxic T-lymphocyte antigen-4 (CTLA-4) targeted antibody, ipilimumab, represents a new standard of care in th...

    Authors: Hannah L. Buckley, Fiona J. Collinson, Gemma Ainsworth, Heather Poad, Louise Flanagan, Eszter Katona, Helen C. Howard, Geraldine Murden, Rosamonde E. Banks, Joanne Brown, Galina Velikova, Tom Waddell, Kate Fife, Paul D. Nathan, James Larkin, Thomas Powles…

    Citation: BMC Cancer 2019 19:1102

    Content type: Study protocol

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  19. The prognostic relevance of circulating tumour cells (CTCs) in metastatic breast cancer (MBC) patients has been confirmed by several clinical trials. However, predictive blood-based biomarkers for stratificati...

    Authors: Natalia Krawczyk, Melissa Neubacher, Franziska Meier-Stiegen, Hans Neubauer, Dieter Niederacher, Eugen Ruckhäberle, Svjetlana Mohrmann, Jürgen Hoffmann, Thomas Kaleta, Malgorzata Banys-Paluchowski, Petra Reinecke, Irene Esposito, Wolfgang Janni and Tanja Fehm

    Citation: BMC Cancer 2019 19:1101

    Content type: Research article

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  20. This study aimed to assess the effect of antibiotics on the clinical outcomes of patients with solid cancers undergoing treatment with immune checkpoint inhibitors (ICIs).

    Authors: Hyunho Kim, Ji Eun Lee, Sook Hee Hong, Myung Ah. Lee, Jin Hyoung Kang and In-Ho Kim

    Citation: BMC Cancer 2019 19:1100

    Content type: Research article

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  21. There are differences in the quality of care among breast cancer patients. Narrowing the quality differences could be achieved by increasing the utilization rate of indicators. Here we explored key indicators ...

    Authors: Chao Wang, Xi Li, Shaofei Su, Xinyu Wang, Jingkun Li, Xiaoqiang Bao and Meina Liu

    Citation: BMC Cancer 2019 19:1099

    Content type: Research article

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  22. Adapting screening strategy to colorectal cancer (CRC) risk may improve efficiency for all stakeholders however limited tools for such risk stratification exist. Colorectal cancers usually evolve from advanced...

    Authors: Laura W. Musselwhite, Thomas S. Redding IV, Kellie J. Sims, Meghan C. O’Leary, Elizabeth R. Hauser, Terry Hyslop, Ziad F. Gellad, Brian A. Sullivan, David Lieberman and Dawn Provenzale

    Citation: BMC Cancer 2019 19:1097

    Content type: Research article

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  23. The aim of this study was to assess the agreement rate between intraoperative evaluation (IOE) and final diagnosis (FD) in a series of surgically resected endometrial carcinoma (EC), with a preoperative ambigu...

    Authors: A. Santoro, A. Piermattei, F. Inzani, G. Angelico, M. Valente, D. Arciuolo, S. Spadola, M. Martini, F. Fanfani, A. Fagotti, V. Gallotta, G. Scambia and G. F. Zannoni

    Citation: BMC Cancer 2019 19:1096

    Content type: Research article

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  24. Circulating extracelluar vesicles (EVs) in epithelial ovarian cancer (EOC) patients emanate from multiple cells. These EVs are emerging as a new type of biomarker as they can be obtained by non-invasive approa...

    Authors: Wei Zhang, Peng Peng, Xiaoxuan Ou, Keng Shen and Xiaohua Wu

    Citation: BMC Cancer 2019 19:1095

    Content type: Research article

    Published on:

  25. The incidence of papillary thyroid carcinoma (PTC) has been increasing worldwide in recent years. Therefore, novel potential therapeutic targets for PTC are urgently needed. Enhancer of zeste homolog 2 (EZH2),...

    Authors: Liqiong Xue, Hongzhu Yan, Ying Chen, Qifa Zhang, Xin Xie, Xiaoying Ding, Xiaojing Wang, Zhongqing Qian, Feng Xiao, Zhiyi Song, Yijie Wu, Yongde Peng and Huanbai Xu

    Citation: BMC Cancer 2019 19:1094

    Content type: Research article

    Published on:

  26. The evasion of apoptosis is a hallmark of cancer. Understanding this process holistically and overcoming apoptosis resistance is a goal of many research teams in order to develop better treatment options for c...

    Authors: Manuela Salvucci, Zaitun Zakaria, Steven Carberry, Amanda Tivnan, Volker Seifert, Donat Kögel, Brona M. Murphy and Jochen H. M. Prehn

    Citation: BMC Cancer 2019 19:1092

    Content type: Review

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  27. The features and survival of stage IV breast cancer patients with different metastatic sites are poorly understood. This study aims to examine the clinicopathological features and survival of stage IV breast c...

    Authors: Ru Wang, Yayun Zhu, Xiaoxu Liu, Xiaoqin Liao, Jianjun He and Ligang Niu

    Citation: BMC Cancer 2019 19:1091

    Content type: Research article

    Published on:

  28. We designed a retrospective study to compare prognostic outcomes based on whether or not surgical resection was performed in elderly patients aged(≥75 years) with resectable pancreatic cancer.

    Authors: Hyeong Min Park, Sang-Jae Park, Sung-Sik Han and Seoung Hoon Kim

    Citation: BMC Cancer 2019 19:1090

    Content type: Research article

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  29. Abnormal autocrine fibroblast growth factor 19 (FGF19) production has been observed in several types of cancers, including hepatocellular carcinoma (HCC). In this study, we investigated the potential of serum ...

    Authors: Takahiro Maeda, Hiroaki Kanzaki, Tetsuhiro Chiba, Junjie Ao, Kengo Kanayama, Susumu Maruta, Yuko Kusakabe, Tomoko Saito, Kazufumi Kobayashi, Soichiro Kiyono, Masato Nakamura, Sadahisa Ogasawara, Eiichiro Suzuki, Yoshihiko Ooka, Shingo Nakamoto, Ryo Nakagawa…

    Citation: BMC Cancer 2019 19:1088

    Content type: Research article

    Published on:

  30. SOX2 is regarded as an important marker in stem cell. The change of SOX2 expression after adjuvant therapy in high grade glioma (HGG) remains unknown so far. Few patients with recurrent glioma have opportunity...

    Authors: Wei Yu, Xiaoqiu Ren, Chunxiu Hu, Yinuo Tan, Yongjie Shui, Zexin Chen, Lili Zhang, Jiaping Peng and Qichun Wei

    Citation: BMC Cancer 2019 19:1087

    Content type: Research article

    Published on:

  31. Cytokeratin 7 (CK7) and GATA binding protein 3 (GATA3) are considered as immunohistochemical hallmarks of breast cancers; however, there are breast tumors lacking these markers. Clinicopathological characteriz...

    Authors: Shaolei Lu, Evgeny Yakirevich, Li Juan Wang, Murray B. Resnick and Yihong Wang

    Citation: BMC Cancer 2019 19:1085

    Content type: Research article

    Published on:

  32. Elevated red blood cell distribution width (RDW) and decreased platelet count (PLT) can be clinically relevant to the prognosis in cancer patients. However, their prognostic values in patients with diffuse lar...

    Authors: Manman Li, Hailong Xia, Huimin Zheng, Yafeng Li, Jun Liu, Linhui Hu, Jingrong Li, Yangyang Ding, Lianfang Pu, Qianle Gui, Yijie Zheng, Zhimin Zhai and Shudao Xiong

    Citation: BMC Cancer 2019 19:1084

    Content type: Research article

    Published on:

  33. Hepatoma-derived growth factor (HDGF) participates in angiogenesis and represents a negative prognostic factor in oral cancer. The current study was designed to elucidate the regulatory mechanism between HDGF ...

    Authors: Yu-Wei Lin, Shih-Tsung Huang, Jian-Ching Wu, Tian-Huei Chu, Shih-Chung Huang, Ching-Chih Lee and Ming-Hong Tai

    Citation: BMC Cancer 2019 19:1083

    Content type: Research article

    Published on:

  34. It remains controversial whether weight change could influence the risks of colorectal cancer (CRC) and mortality. This study aimed to quantify the associations between full-spectrum changes in body mass index...

    Authors: Ji-Bin Li, Sheng Luo, Martin C. S. Wong, Cai Li, Li-Fen Feng, Jian-Hong Peng, Jing-Hua Li and Xi Zhang

    Citation: BMC Cancer 2019 19:1082

    Content type: Research article

    Published on:

  35. Standardized Nucleic Acid Quantification for SEQuencing (SNAQ-SEQ) is a novel method that utilizes synthetic DNA internal standards spiked into each sample prior to next generation sequencing (NGS) library pre...

    Authors: Daniel J. Craig, Thomas Morrison, Sadik A. Khuder, Erin L. Crawford, Leihong Wu, Joshua Xu, Thomas M. Blomquist and James C. Willey

    Citation: BMC Cancer 2019 19:1081

    Content type: Technical advance

    Published on:

  36. The upregulated expression of the JAK/STAT pathway promotes tumor growth in Hodgkin lymphoma (HL) and primary mediastinal large B-cell lymphoma (PMBCL). Based on the hypothesis that JAK2 is a therapeutic targe...

    Authors: Seok Jin Kim, Dok Hyun Yoon, Hye Jin Kang, Jung Yong Hong, Ho Sup Lee, Sung Yong Oh, Ho-Jin Shin, Jee Hyun Kong, Jun Ho Yi, Kana Sakamoto, Young Hyeh Ko, Jooryung Huh, Seung-Sook Lee, Kengo Takeuchi, Dong-Yeop Shin, Cheolwon Suh…

    Citation: BMC Cancer 2019 19:1080

    Content type: Research article

    Published on:

  37. High perioperative morbidity, mortality, and uncertain outcome of surgery in octogenarians with proximal gastric carcinoma (PGC) pose a dilemma for both patients and physicians. We aim to evaluate the risks an...

    Authors: Xuefei Wang, Junjie Zhao, Mark Fairweather, Tingsong Yang, Yihong Sun and Jiping Wang

    Citation: BMC Cancer 2019 19:1079

    Content type: Research article

    Published on:

  38. Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase-derived reactive oxygen species (ROS) not only can promote cancer progression, but also they have recently emerged as mediators of the mucosal immune...

    Authors: Sang Yeon Cho, Sungha Kim, Mi-Ju Son, Gwanghun Kim, Parul Singh, Ha Neul Kim, Hei-Gwon Choi, Heon Jong Yoo, Young Bok Ko, Byung Seok Lee and Hyuk Soo Eun

    Citation: BMC Cancer 2019 19:1078

    Content type: Research article

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  39. BRCA1 associated-protein 1 (BAP1) tumor predisposition syndrome is associated with an increased risk for malignant mesotheliomas, uveal and cutaneous melanomas, renal cell carcinomas, and singular cutaneous lesio...

    Authors: Bianca Costa Soares de Sá, Mariana Petaccia de Macedo, Giovana Tardin Torrezan, Juliana Casagrande Tavoloni Braga, Felipe Fidalgo, Luciana Facure Moredo, Rute Lellis, João Pereira Duprat and Dirce Maria Carraro

    Citation: BMC Cancer 2019 19:1077

    Content type: Case report

    Published on:

  40. To measure changes in four common chemotherapy related side-effects (low energy, stress, nausea and pain) immediately after a single exercise session within the first week after treatment.

    Authors: Anna Johnsson, Ingrid Demmelmaier, Katarina Sjövall, Philippe Wagner, Håkan Olsson and Åsa B. Tornberg

    Citation: BMC Cancer 2019 19:1073

    Content type: Research article

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  41. DNMT3A R882H, a frequent mutation in acute myeloid leukemia (AML), plays a critical role in malignant hematopoiesis. Recent findings suggest that DNMT3A mutant acts as a founder mutation and requires additional g...

    Authors: Xiaodong Shi, Ying Yang, Siqi Shang, Songfang Wu, Weina Zhang, Lijun Peng, Ting Huang, Ruihong Zhang, Ruibao Ren, Jianqing Mi and Yueying Wang

    Citation: BMC Cancer 2019 19:1072

    Content type: Research article

    Published on:

  42. Triple negative breast cancer (TNBC) represents 15–20% of breast cancers. Due to its heterogeneity and high rates of relapse, there is a need to optimize treatment efficacy. Platinum chemotherapy is still cont...

    Authors: Jessa Gilda P. Pandy, Joanmarie C. Balolong-Garcia, Mel Valerie B. Cruz-Ordinario and Frances Victoria F. Que

    Citation: BMC Cancer 2019 19:1065

    Content type: Research article

    Published on:

  43. Prostate cancer is one of the most common cancers in the world. The results of treatment after hypofractionated radiotherapy only have been reported from several small randomized clinical trials. Therefore, we...

    Authors: Wei Guo, Yun-Chuan Sun, Jian-Qiang Bi, Xin-Ying He and Li Xiao

    Citation: BMC Cancer 2019 19:1063

    Content type: Research article

    Published on:

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