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Table 2 Univariate analysis of CIA

From: Incidence of chemotherapy-induced amenorrhea associated with epirubicin, docetaxel and navelbine in younger breast cancer patients

variable

CIA

Age at diagnosis, y

≤40 y

8/63 (12.70%)

>40 y

53/107 (49.53%)

P-value

<0.001

Chemotherapy regimen

FEC

35/78 (44.87%)

TE

20/66 (30.30%)

NE

6/26 (23.08%)

P-value

0.068

Tamoxifen use

Yes

52/117 (44.44%)

No

9/53 (16.98%)

P-value

0.001