From: Incidence of chemotherapy-induced amenorrhea associated with epirubicin, docetaxel and navelbine in younger breast cancer patients
variable
CIA
Age at diagnosis, y
≤40 y
8/63 (12.70%)
>40 y
53/107 (49.53%)
P-value
<0.001
Chemotherapy regimen
FEC
35/78 (44.87%)
TE
20/66 (30.30%)
NE
6/26 (23.08%)
0.068
Tamoxifen use
Yes
52/117 (44.44%)
No
9/53 (16.98%)
0.001