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Table 4 Sensitivity and specificity for the sCD26 at the cut-off value of 460 ng/mL

From: Serum CD26 is related to histopathological polyp traits and behaves as a marker for colorectal cancer and advanced adenomas

Cohort

nsCD26+/nt

Sensitivity (95% CI)

CRC

27/33

81.8% (64.5-93.0)

Advanced adenomas

20/48

41.7% (27.6-56.8)

CRC and advanced adenomas

47/81

58.0% (46.5-68.9)

Non-advanced adenomas and advanced adenomas

30/88

34.1% (24.3-45.0)

Cohort

n sCD26 - / nt

Specificity (95% CI)

No colorectal findings-no symptoms

27/30

90.0% (73.4-97.8)

No colorectal findings

54/68

79.4% (67.9-88.3)

No colorectal findings, non-IBD, IBD, hyperplastic polyps, non-advanced and advanced adenomas

191/264

72.3% (65.0-77.2)

No colorectal findings, non-IBD, IBD, hyperplastic polyps and non-advanced adenomas

163/216

75.5% (68.5-81.0)

  1. nsCD26+: number of individuals with sCD26 levels ≤ 460 ng/mL; nsCD26-: number of individuals with sCD26 levels > 460 ng/mL; nt: total number of individuals per group.