Variables | Total | Cytoplasm | Nucleus | Cytoplasm and Nucleus | ||||||
---|---|---|---|---|---|---|---|---|---|---|
 | N (%) | Negative (%) | Positive | p 1 | Negative (%) | Positive | p 1 | Negative (%) | Positive | p 1 |
Age | Â | Â | Â | 0.019 | Â | Â | 0.405 | Â | Â | 0.060 |
   <51 | 48 (31) | 18 (38) | 30 |  | 28 (58) | 20 |  | 19 (40) | 29 |  |
   51-60 | 52 (34) | 34 (65) | 18 |  | 37 (71) | 15 |  | 32 (62) | 20 |  |
   >60 | 53 (35) | 26 (49) | 27 |  | 34 (64) | 19 |  | 23 (43) | 30 |  |
gender | Â | Â | Â | 0.185 | Â | Â | 0.302 | Â | Â | 0.136 |
   Male | 93 (61) | 43 (46) | 50 |  | 57 (61) | 36 |  | 40 (43) | 53 |  |
   Female | 60 (39) | 35 (58) | 25 |  | 42 (70) | 18 |  | 34 (57) | 26 |  |
Histological grade | Â | Â | Â | <0.001 | Â | Â | <0.001 | Â | Â | <0.001 |
   Well | 53 (35) | 13 (25) | 40 |  | 22 (42) | 31 |  | 12 (23) | 41 |  |
   Moderate | 60 (39) | 38 (63) | 22 |  | 45 (75) | 15 |  | 36 (60) | 24 |  |
   Poor | 40 (26) | 27 (68) | 13 |  | 32 (80) | 8 |  | 26 (65) | 14 |  |
Location | Â | Â | Â | 0.232 | Â | Â | 0.929 | Â | Â | 0.995 |
   Upper | 14 (9) | 5 (36) | 9 |  | 9 (64) | 5 |  | 7 (50) | 7 |  |
   Middle | 101 (66) | 47 (47) | 54 |  | 67 (66) | 34 |  | 49 (49) | 52 |  |
   Lower | 35 (23) | 21 (60) | 14 |  | 22 (63) | 13 |  | 17 (49) | 18 |  |
   Missing | 3 (2) | 2 | 1 |  | 2 | 1 |  | 2 | 1 |  |
Size | Â | Â | Â | 0.238 | Â | Â | 0.973 | Â | Â | 0.843 |
   ≤30 mm | 25 (16) | 11 (44) | 14 |  | 17 (68) | 8 |  | 11 (44) | 14 |  |
   31-60 mm | 105 (69) | 59 (56) | 46 |  | 70 (67) | 35 |  | 53 (51) | 52 |  |
   >60 mm | 14 (9) | 5 (36) | 9 |  | 9 (64) | 5 |  | 7 (50) | 7 |  |
   Missing | 9 (6) | 3 | 6 |  | 4 | 5 |  | 3 | 6 |  |
Lymph node metastasis | Â | Â | Â | 0.090 | Â | Â | 0.727 | Â | Â | 0.398 |
   - | 99 (65) | 45 (46) | 54 |  | 63 (64) | 36 |  | 45 (46) | 54 |  |
   + | 54 (35) | 33 (61) | 21 |  | 36 (67) | 18 |  | 29 (54) | 25 |  |
UICC stage | Â | Â | Â | <0.001 | Â | Â | 0.377 | Â | Â | 0.017 |
   II | 100 (65) | 40 (40) | 60 |  | 62 (62) | 38 |  | 41 (41) | 59 |  |
   III | 53 (35) | 38 (71) | 15 |  | 37 (70) | 16 |  | 33 (62) | 20 |  |
T stage | Â | Â | Â | 0.004 | Â | Â | 0.126 | Â | Â | 0.031 |
   I+II | 44 (29) | 14 (32) | 30 |  | 23 (52) | 21 |  | 14 (32) | 30 |  |
   III | 100 (65) | 57 (57) | 43 |  | 70 (70) | 30 |  | 54 (54) | 46 |  |
   IV | 9 (6) | 7 (78) | 2 |  | 6 (67) | 3 |  | 3 (33) | 6 |  |