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Table 1 IC25 and IC50 values for the effects of VPA on cell growth.

From: Cell type-specific anti-cancer properties of valproic acid: independent effects on HDAC activity and Erk1/2 phosphorylation

Cell Line

IC 25 a(mM)

IC 50 a(mM)

BT4C

1.52

(1.12 - 1.84)

>3.0

-

BT4Cn

1.06

(0.95 - 1.20)

2.67

(2.37 - 2.98)

U87MG

>3.0

-

>3.0

-

N2a

0.65

(0.54 - 0.72)

2.73

(2.11 - 3.19)

PC12-E2

1.83

(1.67 - 1.99)

>3.0

-

CSML0

0.43

(0.24 - 0.53)

1.01

(0.94 - 1.08)

CSML100

0.46

(0.32 - 0.58)

1.22

(0.98 - 1.41)

HeLa

0.70

(0.62 - 0.75)

2.75

(2.54 - 3.01)

Swiss 3T3

1.35

(1.22 - 1.47)

>3.0

-

L929

0.43

(0.32 - 0.51)

1.13

(0.97 - 1.29)

  1. IC 25 and IC 50 values for the effects of VPA on cell growth calculated from interpolations of data. a: Numbers in parentheses indicate interpolated values for IC 25 or IC 50 ± SEM (based on four independent experiments).
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BMC Cancer

ISSN: 1471-2407

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