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Figure 6 | BMC Cancer

Figure 6

From: Clinical array-based karyotyping of breast cancer with equivocal HER2 status resolves gene copy number and reveals chromosome 17 complexity

Figure 6

Proposed algorithm for establishment of HER2 status in breast cancer samples by protein expression and genomic analysis. IHC studies for HER2 protein expression are performed as part of the diagnostic workup and confirmed or resolved by FISH. If FISH and IHC results are concordant, or equivocal IHC results are resolved by FISH, no further testing is done. Equivocal cases by FISH and cases with discordant IHC/FISH results are resolved by array CGH.

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