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Table 5 Effect of non-haplogroup determining mtSNPs on breast cancer, colorectal cancer and thyroid cancer

From: Cancer type-specific modulation of mitochondrial haplogroups in breast, colorectal and thyroid cancer

 

CCS of breast cancer

 

CCS of colorectal cancer

 

CCS of thyroid cancer

 

mtSNPs

Controls

Cases

OR

P value

Controls

Cases

OR

P value

Controls

Cases

OR

P value

 

(N = 114)

(N = 104)

(95%CI)

 

(N = 125)

(N = 108)

(95%CI)

 

(N = 138)

(N = 100)

(95%CI)

 

T16140C

11

7

0.68(0.25-1.81)

0.434

13

14

1.28(0.58-2.87)

0.542

13

7

0.72(0.28-1.89)

0.507

A16182C

11

18

1.96(0.88-4.37)

0.096

18

11

0.67(0.30-1.50)

0.331

15

13

1.23(0.56-2.71)

0.615

A16183C

29

28

1.08(0.59-1.98)

0.803

36

22

0.63(0.34-1.16)

0.138

32

25

1.10(0.61-2.01)

0.747

T16189C

38

35

1.01(0.58-1.78)

0.960

42

36

0.99(0.57-1.71)

0.966

46

26

0.70(0.40-1.24)

0.224

T16217C

16

11

0.72(0.32-1.64)

0.439

17

9

0.58(0.25-1.36)

0.203

19

9

0.62(0.27-1.43)

0.260

C16223T

69

68

1.23(0.71-2.14)

0.458

73

66

1.12(0.66-1.89)

0.674

83

62

1.08(0.64-1.83)

0.772

T16298C

10

12

1.36(0.56-3.29)

0.498

10

14

1.71(0.73-4.03)

0.214

12

6

0.67(0.24-1.85)

0.438

T16304C

11

13

1.33(0.57-3.13)

0.502

23

14

0.66(0.32-1.36)

0.257

28

13

0.59(0.29-1.20)

0.142

T16311C

20

17

0.92(0.45-1.87)

0.814

23

13

0.61(0.29-1.27)

0.180

19

9

0.62(0.27-1.43)

0.260

G16319A

15

13

0.94(0.43-2.09)

0.885

11

18

2.07(0.93-4.61)

0.070

17

16

1.36(0.65-2.83)

0.417

T146C

16

17

1.20(0.57-2.51)

0.634

13

17

1.61(0.74-3.49)

0.225

20

10

0.66(0.29-1.47)

0.303

C150T

28

33

1.43(0.79-2.59)

0.239

33

25

0.84(0.46-1.53)

0.567

33

22

0.90(0.49-1.66)

0.730

T152C

20

23

1.34(0.68-2.61)

0.397

27

26

1.15(0.62-2.13)

0.653

33

31

1.43(0.80-2.55)

0.224

249delA

20

19

1.05(0.53-2.10)

0.889

25

23

1.08(0.57-2.04)

0.807

31

13

0.52(0.25-1.05)

0.063

524delAC

42

27

0.60(0.34-1.07)

0.084

43

33

0.84(0.48-1.46)

0.532

52

42

1.20(0.71-2.0)

0.501

  1. P values were estimated by "chi-square test"; (*) indicated statistical significant (P < 0.05). OR indicates odds ratio; 95% CI, 95% confidence interval.3
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