From: An investigation of breast cancer risk factors in Cyprus: a case control study
Risk factor | Univariable1 | Multivariable (N = 2020)2, 6 | |||
---|---|---|---|---|---|
 |  | OR (95%CI) | p-value3 | OR (95% CI) | p-value3 |
Education | Primary | 1.00 | Â | Â | Â |
 | Secondary | 1.17 (0.96,1.45) |  | 1.18 (0.94,1.48) |  |
 | Tertiary | 1.09 (0.81,1.45) |  | 1.12 (0.81,1.53) |  |
 | University | 1.35 (1.00,1.82) | 0.07 | 1.40 (1.00,1,95) | 0.08 |
Marital status | Married | 1.00 | Â | Â | Â |
 | Widowed/Divorced | 1.08 (0.82,1.42) | 0.57 | 1.06 (0.78,1.44) | 0.84 |
 | Single | 1.55 (1.02,2.34) | 0.04 | 1.28 (0.69,2.35) | 0.43 |
BMI | <25 | 1.00 | Â | Â | Â |
 | 25-30 | 0.80 (0.64,0.98) |  | 0.86 (0.69,1.07) |  |
 | ≥30 | 1.21 (0.96,1.53) | 0.11* | 1.22 (0.95,1.56) | 0.14* |
Family history of breast cancer | No | 1.00 | Â | Â | Â |
 | Yes | 1.68 (1.29,2.19) | <0.001 | 1.64 (1.23,2.19) | 0.001 |
Age at menarche (years) | ≤11 | 1.00 |  |  |  |
 | 12-14 | 0.80 (0.62,1.03) |  | 0.82 (0.62,1.10) |  |
 | ≥15 | 0.61 (0.44,0.84) | <0.01 | 0.64 (0.45,0.92) | 0.01 |
Age at 1st pregnancy (years) | <30 | 1.00 | Â | Â | Â |
 | ≥30 | 1.36 (1.04,1.77) |  | 1.25 (0.93,1.68) | 0.14 |
 | Never4 | 1.51 (1.08,2.12) | <0.01 | 0.93 (0.57,1.54) | 0.76 |
Breastfeeding5 | No | 1.00 | Â | Â | Â |
 | Yes | 0.63 (0.45,0.89) | <0.01 | 0.74 (0.59,0.92) | 0.01 |
Oral contraceptive use | No | 1.00 | Â | Â | Â |
 | Yes | 1.03 (0.86,1.26) | 0.70 | 1.02 (0.83,1.27) | 0.84 |
HRT use (months) | Never | 1.00 | Â | Â | Â |
 | <6 | 0.63 (0.42,0.95) |  | 0.67 (0.42,1.05) |  |
 | 6-60 | 0.49 (0.37,0.65) |  | 0.47 (0.35,0.64) |  |
 | ≥60 | 0.50 (0.34,0.72) | <0.001 | 0.53 (0.35,0.79) | <0.001 |
Exercise | No | 1.00 | Â | Â | Â |
 | Yes | 0.86 (0.72,1.01) | 0.07 | 0.94 (0.78, 1.13) | 0.48 |
Smoking | Never | 1.00 | Â | Â | Â |
 | Past/Current | 1.24 (1.01,1.53) | 0.05 | 1.16 (0.91,1.47) | 0.23 |