Polymorphisms in regulatory regions of Cyclooxygenase-2 gene and breast cancer risk in Brazilians: a case-control study

Table 2 Minor allelic frequency (MAF) of PTGS2 SNPs in Brazilians

SNP	Population	Alleles (N)	MAF (95%CI)	P χ2
rs689465 AG			rs689465 G
	Total *	710	0.17 (0.14-0.20)
	Men	222	0.20 (0.15-0.25)	0.273
	Women	488	0.16 (0.13-0.19)
	Whites	298	0.18 (0.14-0.22)	0.87
	Intermediates	248	0.16 (0.11-0.20)
	Blacks	164	0.16 (0.11-0.22)
rs689466 AG			rs689466 G
	Total *	710	0.13 (0.10-0.15)
	Men	220	0.16 (0.12-0.21)	0.221
	Women	490	0.12 (0.09-0.15)
	Whites	298	0.12 (0.08-0.16)	0.728
	Intermediates	246	0.13 (0.09-0.17)
	Blacks	166	0.15 (0.10-0.21)
rs20417 GC			rs20417 C
	Total *	772	0.30 (0.27-0.33)
	Men	242	0.28 (0.26-0.38)	0.783
	Women	528	0.29 (0.25-0.33)
	Whites	328	0.30 (0.25-0.35)	0.949
	Intermediates	276	0.29 (0.23-0.34)
	Blacks	168	0.31 (0.24-0.38))
rs5275 TC			rs5275 C
	Total *	698	0.30 (0.26-0.33)
	Men	208	0.29 (0.23-0.35)	0.882
	Women	490	0.30 (0.26-0.34)
	Whites	296	0.27 (0.22-0.32)	0.53
	Intermediates	250	0.31 (0.25-0.36)
	Blacks	154	0.34 (0.26-0.41)

ISSN: 1471-2407