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Table 5 Genotypic distribution of PTGS 2 SNPs in cases and controls

From: Polymorphisms in regulatory regions of Cyclooxygenase-2 gene and breast cancer risk in Brazilians: a case-control study

SNP

Population

N*

Genotypic Distribution N (Freq)

P χ2

rs689465

  

AA

AG

GG

 
 

Cases

290

202 (0.69)

83 (0.28)

5 (0.03)

0.927

 

Controls

244

172 (0.70)

67 (0.27)

5 (0.03)

 

rs689466

  

AA

AG

GG

 
 

Cases

289

224 (0.77)

62 (0.21)

3 (0.02)

0.968

 

Controls

245

190 (0.77)

51 (0.21)

3 (0.02)

 

rs20417

  

GG

GC

CC

 
 

Cases

308

157 (0.51)

127 (0.41)

24 (0.08)

0.731

 

Controls

264

129 (0.49)

117 (0.44)

18 (0.07)

 

rs5275

  

TT

TC

CC

 
 

Cases

294

125 (0.42)

149 (0.51)

20 (0.07)

0.046

 

Controls

244

120 (0.49)

99 (0.41)

25 (0.10)

 
  1. N: Number of examined samples (with available PCR amplification); * Differences in sample sizes for cases and controls are due to available data in each category. Freq: Frequency; P χ2: P from Chi-square test (Pearson p-value).