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Table 3 Variable Response Criteria

From: Initial partial response and stable disease according to RECIST indicate similar survival for chemotherapeutical patients with advanced non-small cell lung cancer

Definition of responder

Group

No

Median PFS(95%CI)

P

Dead No.

Median OS(95%CI)

P

≥25% Reduction in tumour

Nonresponder

100

218(176-259)

0.319

86

335(261-408)

0.240

 

Responder

17

289(225-352)

 

14

377(338-415)

 

≥20% Reduction in tumour

Nonresponder

82

218(171-264)

0.874

71

323(276-369)

0.168

 

Responder

35

270(181-358)

 

29

412(328-495)

 

≥15% Reduction in tumour

Nonresponder

66

200(149-250)

0.937

57

323(279-366)

0.323

 

Responder

51

242(190-294)

 

43

385(309-460)

 

≥10% Reduction in tumour

Nonresponder

54

198(127-268)

0.948

47

320(268-371)

0.334

 

Responder

63

225(176-273)

 

53

387(320-453)

 

≥5% Reduction in tumour

Nonresponder

46

218(147-289)

0.789

40

320(272-367)

0.362

 

Responder

71

221(177-265)

 

60

385(317-452)

 

≥0% Reduction in tumour

Nonresponder

17

198(105-291)

0.913

15

323(195-450)

0.448

 

Responder

100

221(193-249)

 

85

350(286-413)

 
  1. 95% CI indicates 95% Confidence Interval; PFS Progression-free Survival; OS Overall survival.