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Table 1 Growth of UV-induced B cell tumors in immune-deficient but not wild type mice

From: Induction of B-cell lymphoma by UVB Radiation in p53 Haploinsufficient Mice

Recipient Mice*

Number of mice

Number with tumor

p‡

Rag2-/-

15

15

_

C57Bl/6

15

1

0.0001

UV-irradiated C57Bl/6†

15

2

0.0001

  1. * 2 × 106 tumor cells were injected into the subcutaneous space of the recipient mice. Tumor growth was monitored daily. Mice were sacrificed when the tumor volume exceeded 1 cm2.
  2. † 10 kJ/m2 UVB radiation, 3x per week for 12 weeks prior to tumor transplantation
  3. ‡ p values determined by Fisher's exact test comparing tumor growth in immune deficient Rag2-/- vs. growth in wild type or UV-irradiated wild type mice.
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BMC Cancer

ISSN: 1471-2407

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