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Table 5 Mutations and clinical findings

From: Hepatitis B virus core promoter mutations G1613A and C1653T are significantly associated with hepatocellular carcinoma in genotype C HBV-infected patients

HCC group 2 (n = 40)

    

Mutation (1613/1653)

-/-

+/-

-/+

+/+

n

14

6

6

14

HBeAg (positive)

40%

60%

50%

67%

Sex (Male)

79%

83%

83%

71%

Patient age

54.6 ± 14.3-

43.3 ± 6.7

57.8 ± 18.3

57.8 ± 9.5

Non-HCC group 2 (n = 52)

    

Mutation (1613/1653)

-/-

+/-

-/+

+/+

n

43

3

3

3

HBeAg (positive)

78%

50%

33%

100%

Sex (Male)

81%

100%

67%

100%

Patient age

37.8 ± 11.0

32.0 ± 17.3

48.7 ± 7.0

30.7 ± 10.2

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BMC Cancer

ISSN: 1471-2407

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